Publications by authors named "Deren Qiang"
Aims: We aimed to evaluate the impact of C-reactive protein (CRP) gene polymorphism, additional gene-gene interaction, and haplotypes on susceptibility to type 2 diabetes mellitus (T2DM).
Methods: SNPstats online software ( https://www.snpstats.
Article Synopsis
- - The study analyzed the connection between depression, diet, and cardiovascular diseases (CVD) in China, using data from 40,925 participants aged 35-70 years from diverse urban and rural communities.
- - Results showed that depressed individuals on unhealthy diets faced a significantly higher risk of CVD incidents and death compared to those on healthy diets, highlighting a notable interaction between depression and dietary habits.
- - The findings emphasize the importance of a healthy diet, particularly increased intake of vegetables and polyunsaturated fatty acids, for those experiencing depression to reduce their risk of premature death and cardiovascular issues.
Smoking causes the disorder of glucose metabolism under different levels of blood pressure in male occupational population.
J Clin Hypertens (Greenwich)
October 2022
Article Synopsis
- Smoking is a modifiable risk factor for type 2 diabetes, with the study examining the impact of smoking on glucose metabolism across various blood pressure levels in working men.
- The analysis included 1,730 male participants and revealed that heavy smokers had higher fasting plasma glucose levels, while moderate to heavy smokers experienced reduced fasting insulin and β-cell function.
- The findings highlight a positive, dose-dependent relationship between smoking intensity and the risk of diabetes and impaired β-cell function, particularly in male workers with elevated blood pressure.
Article Synopsis
- The study investigated cardiovascular disease (CVD) incidence and mortality in China, focusing on the impact of 12 common modifiable risk factors across various demographics.
- The cohort consisted of over 47,000 middle-aged participants, revealing higher CVD rates in men, rural areas, and central/western regions, with CVD being the leading cause of death (36%).
- Modifiable risk factors contributed significantly to CVD and mortality, with hypertension being the most critical risk factor for both outcomes, emphasizing the need for targeted health interventions.
Background & Aims: Although fruits and vegetable consumption has been shown to be associated with lower risks of mortality, cancers, and cardiovascular disease (CVD), there are limited data from China on the shape of the association. This study aimed to quantify the relationship between levels of fruit, vegetable, and legume consumption with the risk of major CVD, CVD mortality, cancer incidence, cancer mortality, and all-cause mortality.
Methods: In the baseline survey, participants attended 1 of 115 (45 urban and 70 rural) communities from 12 provinces to complete a standardized questionnaire, and undergo a physical examination between 2005 and 2009, and were followed up till 2017 (for the current analysis).
Purpose: To determine whether hypertriglyceridemic waist (HTGW) and high lipid accumulation product (LAP) preceded the incidence of type 2 diabetes mellitus (T2DM), and to investigate the interactions of HTGW and LAP with other components of metabolic syndrome on the risk of T2DM.
Methods: A total of 15,717 eligible participants without baseline T2DM and aged 35 and over were included from a Chinese rural cohort. Cox proportional hazards regression models were used to estimate the association of HTGW and LAP with the incidence of T2DM, and the restricted cubic spline model was used to evaluate the dose-response association.