Composition of aerosols from thermal degradation of flavors used in ENDS and tobacco products.

The cardiovascular toxicity of unheated and heated flavorants and their products as commonly present in electronic cigarette liquids (e-liquids) was evaluated previously . Based on the results of assays, cinnamaldehyde, eugenol, menthol, and vanillin were selected to conduct a detailed chemical analysis of the aerosol generated following heating of each compound both at 250 and 750 °C. Each flavoring was heated in a drop-tube furnace within a quartz tube.