Publications by authors named "Derek S Brown"

Introduction: Sexual violence is a significant public health concern with severe physical, social and psychological consequences, which can be mitigated by health service utilisation. However, in Uganda and much of sub-Saharan Africa, these services are significantly underused, with 9 out of 10 survivors not seeking care due to a range of psychological, cultural, economic and logistical factors. Thus, there is a strong need for research to improve health service utilisation for survivors of sexual violence.

View Article and Find Full Text PDF

Background: Little is known regarding economic impacts of intimate partner violence (IPV) in humanitarian settings, especially the labor market burden. Examining costs of IPV beyond the health burden may provide new information to help with resource allocation for addressing IPV, including within conflict zones. This paper measures the incidence and prevalence of different types of IPV, the potential relationship between IPV and labor market activity, and estimating the cost of these IPV-associated labor market differentials.

View Article and Find Full Text PDF

Using a life tables approach with 2011-2017 claims data, we calculated lifetime risks of infection (CDI) beginning at age 18 years. The lifetime CDI risk rates were 32% in female patients insured by Medicaid, 10% in commercially insured male patients, and almost 40% in females with end-stage renal disease.

View Article and Find Full Text PDF

Background: Medicaid-associated disparities in childhood and adolescent (pediatric) cancer diagnosis stage and survival have been reported. However, a key limitation of prior studies is the assessment of health insurance at a single time point. To evaluate Medicaid-associated disparities more robustly, we used Surveillance, Epidemiology, and End Results (SEER)-Medicaid linked data to examine diagnosis stage and survival disparities in those (i) Medicaid-enrolled and (ii) with discontinuous and continuous Medicaid enrollment.

View Article and Find Full Text PDF

Background: Medicare patients and other stakeholders often make health care decisions that have economic consequences. Research on economic variables that patients have identified as important is referred to as patient-centered outcomes research (PCOR) and can generate evidence that informs decision-making. Medicare fee-for-service (FFS) claims are widely used for research and are a potentially valuable resource for studying some economic variables, particularly when linked to other datasets.

View Article and Find Full Text PDF

Background: Limited research has been conducted on cancer-related emergency department (ED) patterns among pediatric cancer patients, including whether there are differences in the characteristics of individuals who seek ED care for cancer complications. The objectives of this study were to determine whether rates and disposition of cancer-related ED visits and hospital admissions in childhood cancer patients differ by sociodemographic factors.

Methods: A cross-sectional analysis of ED encounters with a cancer diagnosis code among patients aged 0-19 years from the 2019 National Emergency Department Sample (NEDS) was conducted.

View Article and Find Full Text PDF

Background: Patients are increasingly interested in data on the economic burdens and impacts of health care choices; caregivers, employers, and payers are also interested in these costs. Although there have been various federal investments into patient-centered outcomes research (PCOR), an assessment of the coverage and gaps in federally funded data for PCOR economic evaluations has not been produced to date.

Objectives: To classify relevant categories of PCOR economic costs, to assess current federally funded data for coverage of these categories, and to identify gaps for future research and collection.

View Article and Find Full Text PDF

Background: Although treatment advances have increased childhood and adolescent cancer survival, whether patient subgroups have benefited equally from these improvements is unclear.

Methods: Data on 42,865 malignant primary cancers diagnosed between 1995 and 2019 in individuals ≤ 19 years were obtained from 12 Surveillance, Epidemiology, and End Results registries. Hazard ratios (HRs) and 95 % confidence intervals (CIs) for cancer-specific mortality by age group (0-14 and 15-19 years), sex, and race/ethnicity were estimated using flexible parametric models with a restricted cubic spline function in each of the periods: 2000-2004, 2005-2009, 2010-2014 and 2015-2019, versus 1995-1999.

View Article and Find Full Text PDF
Article Synopsis
  • * This study tests whether adding a smoke-free homes intervention to quitlines can engage low-income smokers who are not ready to quit and improve long-term cessation rates through data gathered from 211 helplines across 9 states.
  • * By assessing the effectiveness of this dual approach, the research aims to determine if offering smoke-free homes can increase participation in tobacco cessation services and ultimately reduce smoking prevalence among low-income populations.
View Article and Find Full Text PDF

Objective: To evaluate potential effect modification by health insurance coverage on racial and ethnic disparities in cancer survival among US children and adolescents.

Study Design: Data from 54 558 individuals diagnosed with cancer at ≤ 19 years between 2004 and 2010 were obtained from the National Cancer Database. Cox proportional hazards regression was used for analyses.

View Article and Find Full Text PDF
Article Synopsis
  • Globally, 19.7 million children are under-vaccinated, highlighting the need for strategies to reach hard-to-vaccinate populations, particularly in southern Tanzania.
  • In a study of 406 pregnant women, most were willing to pay for vaccinations, with an average willingness to pay of about 3,066 Tsh (around $1.40) for each shot, and preferences leaned towards non-monetary incentives.
  • The findings indicate that while women support timely vaccinations, challenges are more related to systemic barriers than to a lack of demand or interest.
View Article and Find Full Text PDF

Child abuse and neglect is a serious public health issue across the globe, with documented impacts on health, but the impact on hospital costs, at the population level, is unknown. We aimed to estimate the additional public hospital costs for emergency department visits and admitted patient hospitalizations, for persons with reported child protection concerns, from birth to 31 years and modelled to age 65. Using linked hospital data from 2003 to 2017 for a population birth-cohort of all individuals born in South Australia from 1986 to 2017, we estimated costs of public hospital care.

View Article and Find Full Text PDF
Article Synopsis
  • A study aimed to analyze the clinical and financial impacts of inappropriate antibiotic prescriptions for common respiratory infections found that many adults received antibiotics incorrectly; 43%-56% for bacterial and 7%-66% for viral infections.
  • The use of inappropriate antibiotics led to a heightened risk of adverse drug events, such as Clostridioides difficile infections and gastrointestinal issues, with significant hazard ratios indicating increased risks.
  • Additionally, inappropriate prescriptions resulted in higher healthcare costs for patients, with $18-$67 more spent for bacterial infections and variable costs for viral infections.
View Article and Find Full Text PDF

Introduction: Despite evidence suggesting that point-of-care ultrasound (POCUS) is faster and non-inferior for confirming position and excluding pneumothorax after central venous catheter (CVC) placement compared to traditional radiography, millions of chest radiographs (CXR) are performed annually for this purpose. Whether the use of POCUS results in cost savings compared to CXR is less clear but could represent a relative advantage in implementation efforts. Our objective in this study was to evaluate the labor cost difference for POCUS-guided vs CXR-guided CVC position confirmation practices.

View Article and Find Full Text PDF

To achieve the UNAIDS target of diagnosing 95% of all persons living with HIV, enhanced HIV testing services with greater attractional value need to be developed and implemented. We conducted a discrete choice experiment (DCE) to quantify preferences for enhanced HIV testing features across two high-risk populations in the Kilimanjaro Region in northern Tanzania. We designed and fielded a survey with 12 choice tasks to systematically recruited female barworkers and male mountain porters.

View Article and Find Full Text PDF

Background: Racial/ethnic minority children and adolescents are more likely to have an advanced cancer diagnosis compared with non-Hispanic Whites, which may relate to the lack of consistent health care access. This study aims to describe racial/ethnic disparities in cancer diagnosis stage among children and adolescents and assess whether health insurance mediates these disparities.

Methods: Data on individuals ≤19 years of age diagnosed with primary cancers from 2007 to 2016 were obtained from the Surveillance, Epidemiology, and End Results 18 database.

View Article and Find Full Text PDF

Importance: Nonguideline antibiotic prescribing for the treatment of pediatric infections is common, but the consequences of inappropriate antibiotics are not well described.

Objective: To evaluate the comparative safety and health care expenditures of inappropriate vs appropriate oral antibiotic prescriptions for common outpatient pediatric infections.

Design, Setting, And Participants: This cohort study included children aged 6 months to 17 years diagnosed with a bacterial infection (suppurative otitis media [OM], pharyngitis, sinusitis) or viral infection (influenza, viral upper respiratory infection [URI], bronchiolitis, bronchitis, nonsuppurative OM) as an outpatient from April 1, 2016, to September 30, 2018, in the IBM MarketScan Commercial Database.

View Article and Find Full Text PDF
Article Synopsis
  • Efforts to combat the HIV epidemic in Tanzania aim to boost testing rates among high-risk individuals, such as female barworkers and male porters.
  • A discrete choice experiment (DCE) was conducted with 740 participants to gather their preferences regarding six different HIV testing options, analyzing factors like privacy, invasiveness, and accessibility.
  • Results from a sophisticated statistical model revealed diverse preferences among participants, suggesting that tailored interventions could effectively address the unique needs of high-risk populations in HIV testing strategies.
View Article and Find Full Text PDF

Background: Poor child growth and development outcomes stem from complex relationships encompassing biological, behavioral, social, and environmental conditions. However, there is a dearth of research on integrated approaches targeting these interwoven factors. The Grandi Byen study seeks to fill this research gap through a three-arm longitudinal randomized controlled trial which will evaluate the impact of an integrated nutrition, responsive parenting, and WASH (water, sanitation and hygiene) intervention on holistic child growth and development.

View Article and Find Full Text PDF