Publications by authors named "Derek Riffert"
The standard modality for diagnosis of smoke inhalational injury in burn patients is bronchoscopy with or without bronchoalveolar lavage. However, the risks associated with these procedures are poorly described in established literature. We sought to investigate the association between diagnostic bronchoalveolar lavage at admission and the development of pneumonia in burn patients.
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- Thoracic epidural catheters (TECs) provide effective pain management for traumatic rib fractures, but their use is limited by various factors; in contrast, continuous peripheral infusions of ketamine and/or lidocaine offer a safer alternative.
- A study analyzing 1,647 patients found that those receiving TECs had significantly lower daily morphine milligram equivalents (MMEs) and mean pain scores (MPS) compared to those using continuous infusions, especially notable around days 3 and 4 post-injury.
- The findings suggest that drip-only treatment leads to higher pain medication use and pain levels, indicating that TECs might be a more effective pain management option for patients with rib fractures.
Background: Orthotopic liver transplantation (OLT) in patients with cirrhosis complicated by portal hypertension, portosystemic shunts, and chronic portal vein thrombosis (PVT) has long been challenging. Spontaneous spleno-renal shunts (SRS) allow new surgical techniques to restore portal vein patency and hepatopetal flow. Renoportal anastomosis (RPA) has emerged as an accepted method for transplanting these patients, with good long-term patient and graft survival.
View Article and Find Full Text PDFStressed cells downregulate translation initiation and assemble membrane-less foci termed stress granules (SGs). Although SGs have been extensively characterized in cultured cells, the existence of such structures in stressed adult stem cell pools remains poorly characterized. Here, we report that the orthologs of the mammalian SG components AGO1, ATX2, CAPRIN, eIF4E, FMRP, G3BP, LIN-28, PABP and TIAR are enriched in adult fly intestinal progenitor cells, where they accumulate in small cytoplasmic messenger ribonucleoprotein complexes (mRNPs).
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