Publications by authors named "Derek Clougher"

Article Synopsis
  • Mental health disorders are increasingly prevalent in primary care settings worldwide, with a study in Catalonia revealing 18.2% of individuals had at least one mental health diagnosis from 2010 to 2019.
  • The most common diagnoses included unspecified anxiety disorder, insomnia, and unspecified depressive disorder, with an increase in these cases noted until 2015, after which the rates stabilized.
  • Factors such as being female, having a lower socioeconomic status, higher BMI, and smoking were significantly associated with mental health diagnoses, suggesting a need for innovative community-based approaches to address the rising burden of mental health issues.
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Background: Functional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive variables are associated with long-term functional impairment, yet the impact of sex differences is unclear. Functional remediation (FR) is a validated intervention aimed at achieving functional recovery in BD.

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Emotional intelligence (EI) and neurocognition (NC) impairments are common in first-episode psychosis (FEP), yet their evolution over time remains unclear. This study identified patient profiles in EI and NC performance in FEP. 98 adult FEP patients and 128 healthy controls (HCs) were tested on clinical, functional, EI, and NC variables at baseline and two-year follow-up (FUP).

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Older adults with bipolar disorder (OABD) are individuals aged 50 years and older with bipolar disorder (BD). People with BD may have fewer coping strategies or resilience. A long duration of the disease, as seen in this population, could affect the development of resilience strategies, but this remains under-researched.

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Background: Short-term cognitive impairment is associated with SARS-CoV-2 infection but the long-term impact is yet to be examined in detail. We aim to study the evolution of these symptoms in severe COVID-19 patients admitted to the intensive care unit (ICU) between April and December 2020 1 year after hospital discharge and to analyze its clinical correlates.

Method: A total of 58 patients agreed to participate in the 6 months follow-up and 30 at 1 year after hospital discharge.

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Article Synopsis
  • Breast cancer has significant physical and psychological impacts, and while psychosocial interventions show benefits, peer support outcomes have been mixed.
  • This systematic review and meta-ethnography analyzed qualitative evidence from 11 studies with 345 participants, focusing on breast cancer survivors' experiences with peer support.
  • Four key themes emerged: fostering emotional connections, facilitating an educational journey, monitoring emotional experiences among members, and ensuring professional supervision for program quality, providing valuable insights for healthcare professionals to enhance peer support programs.
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Article Synopsis
  • The study investigates how early psychosocial functioning is affected by various factors in first-episode psychosis (FEP), paying particular attention to sex differences among participants.
  • A total of 247 adults with non-affective FEP and 224 healthy controls participated in the study, which assessed their functionality using multiple scales at the beginning and after two years.
  • Results show that while both sexes improved over time, different predictors influenced functioning: for males, longer untreated psychosis and worse premorbid adjustment mattered, whereas for females, processing speed, executive function, and cognitive reserve were key, suggesting tailored interventions based on sex could be beneficial.
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Background: The evolution of cognitive performance throughout the lifespan in bipolar disorder (BD) is understudied. This cross-sectional study aims to describe the cognitive performance across age groups.

Methods: A sample of 654 participants was recruited for this study (BD = 432 and healthy controls -HC- =222).

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Background: Cognitive profiles of BD patients show a demonstrated heterogeneity among young and middle-aged patients, but this issue has not yet deeply explored in Older Adults with bipolar disorder (OABD). The aim of the present study was to analyze cognitive variability in a sample of OABD.

Methods: A total of 138 OABD patients and 73 healthy controls were included in this study.

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Background: Sex differences influence the clinical characteristics and course of illness of bipolar disorder (BD).

Objective: Therefore, the aim of the present study was to examine the role of sex differences in neurocognitive performance and psychosocial functioning in a large sample of euthymic patients suffering from BD.

Methods: The sample included 462 individuals, 347 patients with BD (148 males and 199 females) and 115 healthy controls (HC) (45 males and 70 females).

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