Risk of Nephritis and Recurrence in Kimura Disease: A Retrospective Study.

Background: Kimura disease (KD) presents a diagnostic challenge to clinicians because of its rarity and atypical symptoms in its early stages, and it is difficult to treat and prone to recurrence or involvement of other organs.

Aims And Objectives: This study aims to investigate the possible relevance of renal involvement and recurrence by analysing the clinical presentations, laboratory results, histopathological features, therapeutic data and follow-up results of KD.

Materials And Methods: A total of 27 patients diagnosed as KD in two hospitals from January 1999 to December 2021 were analysed retrospectively in this study based on the diagnosis of histopathology.

Dysbiosis of the Gut Microbiome is associated with Tumor Biomarkers in Lung Cancer.

Lung cancer is a malignancy with high morbidity and mortality worldwide. More evidences indicated that gut microbiome plays an important role in the carcinogenesis and progression of cancers by metabolism, inflammation and immune response. However, the study about the characterizations of gut microbiome in lung cancer is limited.

Blastic plasmacytoid dendritic cell neoplasm of the skin associated with myelodysplastic syndrome.

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a recently described, rare hematologic malignancy with prominent skin involvement. The prognosis of this disease is poor in most cases, with rapid progression despite chemotherapy administration. The first reported case of this disease was in 1994, and less than 200 cases worldwide have been described in the literature to date.

Spontaneous regression of bowenoid papulosis.

A healthy 28-year-old man presented with a 3 month history of multiple papules on the penis that was confirmed as bowenoid papulosis by biopsy. He declined any therapy, but complete resolution was noted 3 months later without any intervention.