Publications by authors named "Deqing Xu"
Polymorphisms of myostatin (MSTN) gene were investigated as a candidate marker for goat growth in 687 individuals by gene sequencing and polymerase chain reaction restriction fragment length polymorphism methods. Three potential genotypes (AA, AB and BB) of 5 bp indel (1,256 TTTTA/-) in 5'UTR were detected in four breeds. The polymorphism (CC, CD and DD) of substitution (1,388 T/A) in exon 1 was only segregating in Boer.
View Article and Find Full Text PDFTwo active mutations (A 781 G and A 1575 G) in growth hormone (GH) gene, and their associations with litter size (LS), were investigated in both a high prolificacy (Matou, n = 182) and a low prolificacy breed (Boer, n = 352) by using the PCR-RFLP method. Superovulation experiments were designed in 57 dams, in order to evaluate the effect of different genotypes of the GH gene on superovulation response. Two genotypes (AA and AB, CC and CD) in each mutation were detected in these two goat breeds.
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- Skin lesions in systemic lupus erythematosus (SLE) are common, but the exact cause and role of DNA in these lesions remains unclear; this study investigates this relationship.
- The researchers examined skin samples from SLE patients and used various methods to analyze extracellular DNA found in the lesions, discovering that DNA was only present in affected skin areas, not in normal or non-lesion skin.
- Results indicated that DNA fragments correlated with disease activity, suggesting that DNA and immune complexes play a role in the development of skin lesions in SLE, with significant homology to human DNA, but not microbial DNA.