Association between psychological resilience, social support and oral health behaviours in patients with implant dentures.

Background: With the improvement of living standards, implant dentures have become the choice of more and more patients with missing teeth. Dentures are not natural teeth, and may cause different degrees of negative impacts on patients in physiological, psychological and social aspects. The objective of this study was to examine the current status of psychological resilience among implant denture patients and the factors that influence it.

[Comparison of the repair effects of Haiao oral biofilm alone or in combination with allogeneic bone graft in bone defects after jaw bone cyst surgery].

Purpose: To compare the repair effects of Haiao oral biofilm alone or in combination with allogeneic bone graft on bone defects after jaw bone cyst surgery.

Methods: A prospective study was conducted on 105 patients with bone defects after jaw bone cyst surgery who were admitted to Affiliated Hospital of Jiangnan University from November 2020 to July 2022. According to the random number table methods, the patients were divided into three groups: Haiao membrane group, allogeneic bone graft group and combination group.

circFNDC3B Accelerates Vasculature Formation and Metastasis in Oral Squamous Cell Carcinoma.

Unlabelled: Emerging evidence has demonstrated that circular RNAs (circRNA) are involved in cancer metastasis. Further elucidation of the role of circRNAs in oral squamous cell carcinoma (OSCC) could provide insights into mechanisms driving metastasis and potential therapeutic targets. Here, we identify a circRNA, circFNDC3B, that is significantly upregulated in OSCC and is positively associated with lymph node (LN) metastasis.

Precise extraction of impacted supernumerary tooth in the maxillary anterior region with a digital guide plate: A case report.

Rationale: Removal of impacted supernumerary teeth requires precision and accuracy to prevent iatrogenic injury to important anatomical structures during dental surgery and to improve postoperative healing.

Patient Concerns: A 12-year-old girl visited our department for the assessment and management of her deviated front teeth.

Diagnosis: Impacted supernumerary tooth extraction in the maxillary anterior region.

NOD1 activation promotes cell apoptosis in papillary thyroid cancer.

Background: NOD1 can promote or inhibit different types of cancers, suggesting that NOD1 functions in the progression of cancers dependent on the tumour environment. However, the expression and mechanisms of NOD1 during papillary thyroid carcinoma (PTC) progression remain unclear.

Methods: To investigate the role of NOD1 in PTC development and apoptosis, we detected NOD1 expression in three cell lines and surgical specimens from patients with PTC using immunohistochemistry, quantitative real-time PCR (Q-PCR) and Western blotting; we studied the biological functions of NOD1 by loss-of-function analysis of TPC-1 and BCPAP cells and the effect of NOD1 on the progression of PTC in terms of cell proliferation and apoptosis induced by tumour necrosis factor alpha (TNF-α), Fas ligand (Fas L), tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) or Ala-γGlu-diaminopimelic acid (TriDAP) in the presence of cycloheximide (CHX) and determined its underlying molecular mechanism using PTC cell lines in vitro and mouse xenograft models in vivo.

MiR-376c-3p targets heparin-binding EGF-like growth factor (HBEGF) to inhibit proliferation and invasion in medullary thyroid carcinoma cells.

Introduction: Aggressive medullary thyroid carcinomas (MTC) have a high mortality rate and the treatment for patients diagnosed with advanced MTC is comparatively ineffective. We hence aimed to test the effects of miR-376c-3p on MTC and to explore the relevant mechanism.

Material And Methods: Cell Counting Kit-8 (CCK-8) and soft agar colony formation assay were applied to evaluate the proliferation of transfected MZ-CRC-1 cells.

TLR2 deficiency enhances susceptibility to oral carcinogenesis by promoting an inflammatory environment.

Inflammation is closely related to oral squamous cell carcinoma (OSCC). However, its mechanism is still obscure. Toll-like receptor 2 (TLR2) plays an important role in oral chronic inflammatory diseases, but the role of TLR2 in OSCC is unclear.

Mir-5100 Mediates Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells Via Targeting SCAI.

Purpose: We aimed to investigate the role of microRNA-5100 (miRNA-5100) in oral squamous cell carcinoma (OSCC) and its underlying mechanisms. The expression of miR-5100 and suppressor of cancer cell invasion (SCAI) in OSCC cell lines were examined. A luciferase reporter assay was applied to confirm the combination between miR-5100 and SCAI.

High expression of TROP2 is correlated with poor prognosis of oral squamous cell carcinoma.

Human trophoblastic cell-surface antigen 2 (TROP2) is a cell surface glycoprotein that exhibits high expression in various carcinomas but low or no expression in normal tissues. High TROP2 expression plays an important role in promoting tumor development and aggressiveness, which is correlated with reduced patient survival. However, there are few studies regarding TROP2 in relation to both oral squamous cell carcinoma (OSCC) and oral potentially malignant lesions.