Publications by authors named "Denzil May"
Article Synopsis
- A late 20s female patient experienced severe pain in the upper abdomen, prompting concern for possible gastrointestinal perforation.
- A CT scan revealed perigastric appendagitis, a rare condition that can cause significant abdominal pain.
- The patient was successfully treated with pain medication, did not need surgery, and was discharged the following day.
Aim: To determine a cost-efficient strategy for HNPCC molecular diagnostic testing.
Methods: 138 families referred to a Regional Genetics Service had hMLH1 and hMSH2 mutation analysis. The sensitivity and specificity of clinical selection criteria with or without immunohistochemistry (IHC) and microsatellite instability (MSI) analysis to further refine case selection and the effect of these approaches on the cost of mutation analysis were examined.