Publications by authors named "Denogratov S"

Objective: Bone loss is an established reaction to diminished muscular activity (Hypokinesia; HK). It has been assumed that periodic fluid redistribution (PFR) could contribute to vascular volume. The fluid volume expansion would then increase tissue perfusion.

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Objective: Fluid redistribution (FR) is an important cornerstone in treating diseases. Findings of FR with periodic head down tilt (PHDT) had sparked renewed interest in treating electrolyte disturbances. Therefore this study aimed to determine the potential benefits of potassium (K+) deposition with periodic FR by PHDT during diminished muscular activity (hypokinesia; HK).

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Measuring intercompartmental, blood and urinary biochemical parameters during acute bed rest (ABR) and rigorous bed rest (RBR) the aim of this work was to disclose if ABR or RBR could influence significantly more and significantly faster the body hydration level in normal subjects. Studies conducted during pre-bed rest (BR) period of 3-days and during 7-days period of ABR and RBR. Thirty normal male individuals 24.

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Rigorous bed rest (RBR) induces fluid depletion, however, little is known about the mechanisms of development of fluid depletion during acute bed rest (ABR). Measuring fluid retention and body hydration parameters, the aim of this study was to establish whether ABR than RBR could depress significantly more fluid retention contributing to greater fluid depletion development. Studies were conducted during pre bed rest (BR) period of three days and during seven days period of ABR and RBR.

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Background: Hypokinesia (reduced motor activity) induces significant tissue morphological changes, however, it is not known if hypokinesia (HK) could contribute to morphological changes in the kidney. Measuring the nuclear size in the inner medullary collecting ducts on the kidney of rats the aim of this investigation was to disclose kidney morphological changes during prolonged HK.

Methods: Studies were done on 192 13-week-old male rats (370 to 390 g) during 15 days pre-HK period and 90 days HK period.

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Hypokinesia (decreased motor activity) induces significant morphological changes in the kidneys, but little is known about the effect of hypokinesia (HK) on the collecting duct nuclei of the kidney. The aim of this study was to measure the effect of prolonged HK on the nuclear size in the inner meduallary collecting ducts on the kidney of rats. Studies were done on one hundred ninety-two 13-week-old male rats (370 to 390 g) during 15 days pre HK period and 90 days HK period.

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Hypokinesia (HK) (diminished movement) induces significant electrolyte changes, but little is known about the effect of periodic hypokinesia (PHK) on minerals. The aim of this study was to measure the effect of PHK and continuous hypokinesia (CHK) on urinary and serum electrolytes. Studies were done during a 30-d period of prehypokinesia (HK) and during 364 d of PHK and CHK periods.

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