Publications by authors named "Dennis Robertson"
Background: Photodynamic therapy (PDT) has been used occasionally as an alternative treatment for uveal melanomas. The present study describes the clinical and histopathologic features of five choroidal melanomas after PDT.
Methods: Three patients with pigmented choroidal melanomas were treated with PDT and intravitreal bevacizumab 1 week before undergoing biopsy and brachytherapy to minimize the risks of bleeding during the biopsy.
Purpose: To estimate the long-term cumulative risk of retinal detachment (RD) after cataract extraction.
Methods: Using the resources of the Rochester Epidemiology Project, we retrospectively identified all residents of Olmsted County, Minnesota, who had cataract extraction from 1980 through 2004 (10,256 cataract extractions in 7,137 residents) and were diagnosed with RD. The observed probability of RD after cataract extraction was estimated using the Kaplan-Meier method.
Purpose: To estimate the long-term cumulative risk of retinal detachment (RD) after cataract extraction (CE).
Design: Retrospective cohort study and nested case-control study.
Participants: All residents of Olmsted County, Minnesota who had CE from 1980 through 2004 (10 256 CEs in 7137 residents) and were diagnosed subsequently with RD in the same period.
Objective: To report our longer-term follow-up observations in patients with small choroidal melanomas primarily treated with transpupillary thermotherapy (TTT).
Methods: In this noncomparative interventional case series, 40 patients with small melanocytic tumors of the choroid (thickness <3.5 mm) underwent TTT.
Objective: To describe the time between treatment for choroidal melanoma and first diagnosis of metastatic disease, sites of metastasis, treatments for metastasis, and time between diagnosis of metastasis and death.
Design: Prospective, longitudinal follow-up of patients diagnosed with choroidal melanoma who were enrolled in 2 randomized trials conducted by the Collaborative Ocular Melanoma Study Group.
Methods: Systemic and laboratory evaluations were performed during follow-up according to a standard protocol for 2320 patients enrolled in the Collaborative Ocular Melanoma Study trials without evidence of melanoma metastasis or other primary cancer at baseline.
Radiation complications and tumor control after 125I plaque brachytherapy for ocular melanoma.
Int J Radiat Oncol Biol Phys
September 2005
Purpose: To determine the outcome of 125I plaque brachytherapy at our institution and identify the risk factors associated with the development of radiation complications, tumor recurrence, and metastasis.
Patients And Methods: From 1986 to 2000, 156 patients underwent 125I episcleral plaque (COMS design) application for the treatment of ocular melanoma. Chart analysis of follow-up ophthalmologic appointments assessed the incidence of ocular side effects after therapy.
Objective: To report retinopathy following exposure to light from a commercially available class 3A green laser pointer.
Methods: A 55-year-old woman with a ring melanoma was scheduled for enucleation. The eye (visual acuity 20/20) had a healthy-appearing macular retina.
Objective: To report sites of second primary cancer and the time to first diagnosis during routine follow-up after treatment for choroidal melanoma.
Design: Prospective longitudinal follow-up of patients enrolled in 2 randomized trials conducted by the Collaborative Ocular Melanoma Study (COMS) Group.
Methods: Baseline and annual or semiannual systemic and laboratory evaluations were performed according to a standard protocol for 2320 patients enrolled in the COMS without evidence of melanoma metastasis or other primary cancer at baseline.
Purpose: To describe the predictive value of liver function tests (LFTs), chest x-ray, and diagnostic imaging for detecting melanoma metastasis during routine follow-up after treatment for choroidal melanoma.
Materials And Methods: Prospective longitudinal follow-up of patients enrolled onto two randomized trials was conducted by the Collaborative Ocular Melanoma Study (COMS) Group. Baseline and annual or semiannual systemic and laboratory evaluations were performed according to a standard protocol for 2320 patients enrolled on the COMS.
Purpose: To determine the incidence of postoperative systemic complications and nonophthalmic reasons for prolonged hospitalization after vitreoretinal procedures performed under general anesthesia.
Methods: Patient charts of vitreoretinal or ocular oncologic surgical cases performed under general anesthesia between 1996 and 2001 were reviewed retrospectively. Occurrences of postoperative systemic events within 4 weeks of surgery were documented.
TTT as rescue treatment for choroidal melanoma not controlled with iodine-125 brachytherapy.
Ocul Immunol Inflamm
December 2002
Purpose: To describe the use of transpupillary thermotherapy in the management of two small choroidal melanomas that continued to grow following Iodine-125 brachytherapy.
Methods: Case reports from a tertiary care center.
Results: One small growing choroidal melanoma showed a partial response to Iodine-125 brachytherapy; four years later, it regrew to a thickness of 2.
Purpose: To review emerging information related to changing concepts in the management of choroidal melanoma.
Design And Methods: This perspective reviews and discusses selected studies from the past two decades that have influenced management strategies for large, medium, and small-size choroidal melanomas.
Results: Large choroidal tumors continue to be managed primarily by enucleation.
Background: A prospective study was conducted to determine if external ionizing radiation could favorably influence the orbital manifestations of Graves ophthalmopathy. Diabetes and untreated systemic hypertension were exclusion criteria. Radiation was directed to the orbits of 42 affected patients using 0.
View Article and Find Full Text PDFObjective: To describe the use of a polymethylmethacrylate contact lens as an artificial cornea to enhance visualization for practice surgery using cadaver eyes.
Design: The opaque cornea of a cadaver eye is removed by trephination. Cyanoacrylate glue is used to secure a large-diameter polymethylmethacrylate contact lens to the corneal rim.
This survey reviews selected medical disorders in which the ophthalmologist has a unique opportunity of anticipating the existence of asymptomatic, life-threatening disease simply by recognizing that certain benign conditions involving the eye or adnexa represent clues to occult non-ocular cancer and other neoplasias. Having knowledge that these clues are associated with specific types of neoplasia, the ophthalmologist can then initiate a goal-directed oncologic investigation designed to identify the underlying neoplasm with the hope of providing potentially life-saving therapy. The survey is organized to feature each clue separately.
View Article and Find Full Text PDFObjective: To determine whether long-term improvement could be observed after orbital radiotherapy for Graves' disease; in addition, to evaluate ancillary treatments needed for those who have received radiotherapy, to search for late-emerging adverse consequences of radiotherapy, and to relate orbital changes to serum levels of thyroid-stimulating immunoglobulin (TSI).
Design: Three-year follow-up of noncomparative interventional case series.
Participants: Forty-two patients.