Publications by authors named "Dennis Ks Law"

Background: Serogroup B Neisseria meningitidis (MenB) has always been a major cause of invasive meningococcal disease (IMD) in Canada. With the successful implementation of a meningitis C conjugate vaccine, the majority of IMD in Canada is now caused by MenB.

Objective: To investigate IMD case isolates in Atlantic Canada from 2009 to 2013.

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Article Synopsis
  • Researchers amplified and sequenced the quinolone resistance-determining regions of gyrA and parC in Haemophilus parainfluenzae strains.
  • Similar to another bacteria, Haemophilus influenzae, quinolone resistance in H. parainfluenzae is linked to mutations in these genes.
  • The study emphasizes the significance of understanding these mutations for tracking antibiotic resistance.
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Three group B Neisseria meningitidis isolates, recovered from meningococcal disease cases in Canada and typed as B:2c:P1.5, were characterized. Multilocus sequence typing showed that all three isolates were related because of an identical sequence type (ST) 573.

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