Publications by authors named "Dennis J A J Oerlemans"

Background: Observational studies indicate a potential association between diabetes medication use and aggressiveness of bladder cancer.

Objective: The objective is to exploratively study the association between diabetes medication use, as proxy for diabetes, and cancer characteristics of urothelial carcinoma at diagnosis. Furthermore, differences in associations between specific types of diabetes medication are studied.

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Article Synopsis
  • The study aimed to assess how a web-based decision aid (DA) influences treatment preferences in patients with lower urinary tract symptoms related to benign prostatic hyperplasia (LUTS/BPH).
  • A total of 126 patients participated, with a significant number undecided about their treatment options before using the DA; half of these decisional patients established a preference after using it.
  • Most patients who had an initial treatment preference reaffirmed it after using the DA, and healthcare providers expressed positive views on the DA’s usability and effectiveness in guiding treatment choices.
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Article Synopsis
  • The study aimed to evaluate the effectiveness of a web-based decision aid for men suffering from lower urinary tract symptoms due to benign prostatic hyperplasia, comparing it to usual care.
  • Men using the decision aid were found to make better-informed treatment choices and had a clearer understanding of their decisions compared to those who did not use the aid.
  • Results indicated that decision aid users experienced less decisional conflict, had a more active role in decision-making, and were more likely to opt for lifestyle interventions over medication.
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Introduction: Sacral neuromodulation (SNM) of the lower urinary tract has proven to be safe and effective in patients with complaints of OAB syndrome who are not responding to conservative therapy. After 5 years of treatment the implanted system is still effective in 56-71% of patients. The loss of effect could be caused by adaptation of the nerve system to prolonged stimulation of the sacral nerves.

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Patients with symptoms of overactive bladder syndrome or non-obstructive urinary retention, refractory to conservative therapy, can nowadays be treated minimally invasively with sacral nerve stimulation (SNS). The use of electric currents to treat urological pathology has a long history but SNS therapy only received FDA approval in 1997. The mechanisms of action are still not known so there are different theories explaining the modulation effect.

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Objective: To describe patient selection for sacral neuromodulation, also known as Interstim therapy, and the results of tined-lead implantation in the medium term.

Patients And Methods: In all, 49 patients, 39 with refractory overactive bladder symptoms and 10 with urinary retention, were implanted with the tined lead under local anaesthesia. The mean (sd) test period was 12.

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