Publications by authors named "Dennis I Brown"
Article Synopsis
- Microglia are crucial for protecting the central nervous system and removing harmful substances, but their function declines with age, leading to increased neurological issues like multiple sclerosis.
- Researchers used advanced techniques on spinal cord samples from young and middle-aged mice to understand how aging affects microglial behavior, particularly after injury.
- They discovered that an increase in osteopontin in older mice worsens neurodegeneration, while reducing this protein can help alleviate inflammation and damage in aging-related conditions.
