Publications by authors named "Dennis G Crandall"

Background: Three-column spinal osteotomies (3-CO) are powerful techniques used to correct spinal deformity. These surgeries are associated with an elevated risk of complications. While outcomes have been reported in the literature with 2 years follow-up, longer-term outcomes of three-column osteotomies remain understudied.

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Study Design: Retrospective study of a prospectively collected database at one center.

Objectives: Assess the outcomes and complications of adult spinal deformity (ASD) surgery in patients that are 75 years and older compared with patients of 65-75 years of age. With increasing amounts of ASD surgery being performed on elderly patients, it is important to assess how age plays a factor in corrective reconstruction surgery.

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Background: High complication rate has been documented in spinal instrumentation with pedicle subtraction osteotomy. The objective was to analyze the biomechanics of spinal instrumentation with pedicle subtraction osteotomy as functions of three instrumentation parameters.

Methods: Patient-specific biomechanical computer models of 3 adult patients who were instrumented with pedicle subtraction osteotomy were used to simulate the actual instrumentations and alternative instrumentations derived by varying instrumentation parameters: pedicle subtraction osteotomy wedge angle and rod contouring angle, location of the osteotomy, and number of rods (2 vs.

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Background: This trial reports the 2-year and immediate postremoval clinical outcomes of a novel posterior apical short-segment (PASS) correction technique allowing for correction and stabilization of adolescent idiopathic scoliosis (AIS) with limited fusion.

Methods: Twenty-one consecutive female AIS patients were treated at 4 institutions with this novel technique. Arthrodesis was limited to the short apical curve after correction with translational and derotational forces applied to upper and lower instrumented levels.

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Background: Efforts to select the appropriate number of implants in adolescent idiopathic scoliosis (AIS) instrumentation are hampered by a lack of biomechanical studies. The objective was to biomechanically evaluate screw density at different regions in the curve for AIS correction to test the hypothesis that alternative screw patterns do not compromise anticipated correction in AIS when using a segmental translation technique.

Methods: Instrumentation simulations were computationally performed for 10 AIS cases.

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Study Design: Retrospective cohort analysis of prospectively collected data.

Objective: To determine whether an association exists between body mass and surgical outcomes in patients with degenerative scoliosis after long instrumented spinal arthrodesis (≥ 4 discs).

Summary Of Background Data: Obesity is thought to be associated with increased surgical complications and inferior clinical outcomes in adults.

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Study Design: Retrospective cohort study.

Objective: To determine whether an association exists between high body mass index (BMI>25 kg/m) and surgical outcomes in revision adult scoliosis patients.

Summary Of Background Data: Obesity is thought to be associated with increased surgical complications and inferior clinical outcomes in adults.

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Study Design: Retrospective cohort analysis of prospectively collected data.

Objective: To compare clinical outcomes and postoperative complications in patients with lumbar degenerative scoliosis who underwent primary (P) versus revision (R) surgery.

Summary Of Background Data: Revision surgery for spinal deformity is technically challenging and may be associated with greater risks of complications and inferior clinical outcomes.

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Study Design: Retrospective clinical study of a prospective database.

Objective: This study aims to determine whether revision spinal fusion surgery is worthwhile in patients older than 75 from a risk-benefit perspective.

Summary Of Background Data: The benefits of spinal fusion in patients older than 65 is well documented.

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Background Context: Novel dual-threaded screws are configured with overlapping (doubled) threads only in the proximal shaft to improve proximal cortical fixation.

Purpose: Tests were run to determine whether dual-threaded pedicle screws improve pullout resistance and increase fatigue endurance compared with standard pedicle screws.

Study Design/setting: In vitro strength and fatigue tests were performed in human cadaveric vertebrae and in polyurethane foam test blocks.

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Study Design: Retrospective review of prospectively collected data.

Objective: To evaluate long-term clinical outcomes and complications of the transforaminal lumbar interbody fusion (TLIF) procedure from a large consecutive series, without industry funding. Clinical outcomes and complications are analyzed by diagnosis and primary versus revision surgery to assess whether TLIF with bone morphogenic protein (BMP) is appropriate for common use in deformity, spondylolisthesis, and degenerative disease.

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Study Design: Retrospective review of prospectively collected data.

Objective: Without industry funding, the study evaluated short- and long-term complications related to off-label bone morphogenetic protein (BMP) used with transforaminal lumbar interbody fusion (TLIF) from a large consecutive series. Complications and results were analyzed by BMP dose, fusion length, and primary versus revision surgery.

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Study Design: Prospective, nonrandomized consecutive single surgeon series.

Objective: To compare the clinical and radiographic outcomes in degenerative lumbar scoliosis (DLS) patients treated with posterior instrumented correction and fusion with additional anterior lumbar interbody fusion (ALIF) versus transforaminal lumbar interbody fusion (TLIF) to help define whether anterior surgery should be routinely required in treating DLS.

Summary Of Background Data: The benefits of interbody support in promoting postoperative stability and arthrodesis are well established.

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