Changes in the activity of Cu/Zn superoxide dismutase, lipid profile and aorta morphology of spontaneously hypertensive rats on zinc diet.

Unlabelled: The aim of the present study was to investigate the effect of zinc on the activity of copper-zinc superoxide dismutase (Cu/Zn SOD), the lipid profile, the arterial blood pressure and the morphological changes of the aorta in male spontaneously hypertensive rats (SHR).

Materials And Methods: The study included 52 male SHR animals. The animals were randomly asigned into three groups to be fed one of three zink diets--in group one animals (G1, control group) the zinc content was 50 mg/kg, in group two (G2)--155 mg/kg and in group three (G3) 250 mg/kg.

Effect of zinc on the activity of Cu/Zn superoxide dismutase and lipid profile in Wistar rats.

Aim: The aim of the present study was to analyze the effect of zinc on the activity of Cu/ZnSOD, lipid profile and arterial blood pressure in male Wistar rats.

Material And Methods: The study included 53 male Wistar rats with basal weight 190-210 g. The animals were divided into three groups and put on diets with different zinc content.