Results of 1001 liver transplantations in 23 years: Ege University experience.

Background/aims: Liver transplantation (LT) is now the standard of care for most end-stage liver diseases. Over the next 30 years, advances in medicine and technology will greatly improve the survival rates of patients after this procedure. The aim of the present study was to analyze retrospectively the results of 1001 patients withLT.

Suppression of atherogenesis by n-3 fatty acids in the cholesterol-fed rabbit.

The effects of n-3 fatty-acid supplementation on serum lipids, platelet aggregation, and the development of atherosclerotic lesions were studied in the cholesterol-fed rabbit. Serum total cholesterol and LDL cholesterol values were significantly reduced in comparison with those of the nonsupplemented cholesterol-fed group (p less than 0.005, p less than 0.

The effect of vitamin E on glycosylated hemoglobin levels in diabetic rats: a preliminary report.

The effect of vitamin E (D-alpha-tocopherol acetate) on glycosylated hemoglobin levels was investigated in streptozotocin-diabetic rats. The animals were divided into four groups: (a) Group 1: control group, (b) Group 2: diabetic group, (c) Group 3: diabetic group treated with low-dose vitamin E and (d) Group 4: diabetic group treated with high-dose vitamin E. Starting 24 hr after streptozotocin injections (60 mg/kg), Groups 3 and 4 received intraperitoneal injections of vitamin E on days 1, 4, 7, 11, 14, 18 and 21 at doses of 500 mg/kg and 1,000 mg/kg respectively.

Modulation of gamma-glutamyl transpeptidase activity by dietary eicosapentaenoic acid and vitamin E in livers of rabbits on hypercholesterolemic diet.

Rabbits were fed high-cholesterol diets containing either eicosapentaenoic acid (EPA) or vitamin E at doses of 80 mg and 100 IU per day, respectively. Liver gamma-glutamyl transpeptidase (GGT) activity and liver cholesterol and phospholipid levels were determined following the administration of the diets for 45 days. The feeding of cholesterol produced the highest concentrations of cholesterol in livers accompanied with the elevated enzymatic activity.

Influence of eicosapentaenoic acid and vitamin E on brain cortex Ca2+ ATPase activity in cholesterol-fed rabbits.

The influence of eicosapentaenoic acid (EPA) and vitamin E on brain cortex Ca2+ ATPase activity was examined in rabbits receiving cholesterol-rich diets for a period of 45 days. Rabbits were divided as control (A) and cholesterol-fed groups (B, C, and D). Group C received 80 mg of EPA and group D received 100 IU of vitamin E every day in addition to the cholesterol-rich (2%, w/w) diet which was solely given to Group B.