Plant-Produced Glycosylated and In Vivo Deglycosylated Receptor Binding Domain Proteins of SARS-CoV-2 Induce Potent Neutralizing Responses in Mice.

The COVID-19 pandemic, caused by SARS-CoV-2, has rapidly spread to more than 222 countries and has put global public health at high risk. The world urgently needs cost-effective and safe SARS-CoV-2 vaccines, antiviral, and therapeutic drugs to control it. In this study, we engineered the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) protein and produced it in the plant in a glycosylated and deglycosylated form.

Effect of Health Literacy on Health Perception: An Application in Individuals at Age 65 and Older.

This study has been conducted to look through the effects of health literacy levels of individuals age 65 years and older on their health perceptions. The application part of study is composed of persons being age 65 years or older who live in Burdur province and districts of Turkey. The sampling of study has been determined by a nonclustered, single-step random probability sampling method based on primary mass ratios.