Publications by authors named "Deniz Ozberk"
Article Synopsis
- Opioids are drugs used to help relieve moderate to severe pain in people with advanced cancer, but different patients react to them in unexpected ways.
- Researchers want to understand how a specific gene, KCNJ6, affects how well patients respond to a type of opioid called methadone for pain relief.
- In a study with 54 cancer patients, they found no clear link between the KCNJ6 gene and how much methadone was needed or the level of pain relief, which is similar to other research in this area.
Pharmacogenomics
April 2022
Article Synopsis
- * Previous research indicates that specific genetic variations (polymorphisms) may affect how patients respond to methadone.
- * A recent study found significant links between certain genetic markers and methadone dosage and pain severity, suggesting that genetic testing could help tailor pain management in cancer patients.
