Predictors of 2-year mortality in geriatric patients hospitalized with COVID-19 in Türkiye: a retrospective cohort study.

To reveal factors affecting 2-year mortality in geriatric patients hospitalized with COVID-19. Demographic characteristics, clinical and laboratory data, thorax computed tomography (CT) images, second-year survival status, and causes of death were analyzed. The 2-year post-discharge mortality rate of 605 patients was 21.

Insights into geriatric health: primary sarcopenia and innate immunity dynamics, examining SARC-F, serum TLR 4, TLR 9, and resolvin levels.

The aim of this study is to evaluate the relationship between serum TLR (Toll Like Receptor) 4, 9 and Resolvin E1 levels and primary sarcopenia in geriatric patients and to compare the diagnostic accuracy of these biomarkers with the SARC-F score. A total of 88 patients aged 65 years and older were evaluated in the study. Comorbidities and geriatric syndromes were identified and patients with secondary sarcopenia were excluded.

The Role of NF-κB, PPAR-α, and PPAR-γ in Older Adults with Metabolic Syndrome.

The etiopathogenesis of metabolic syndrome (MetS) has not been fully understood yet, and chronic low-grade inflammation is thought to be associated with the development of complications related to MetS. We aimed to investigate the role of Nuclear factor Kappa B ( NF-κB ), Peroxisome Proliferator-Activated Receptor- α and γ (PPAR-α, and PPAR-γ) which are the main markers of inflammation in older adults with MetS. A total of 269 patients aged≥18, 188 patients with MetS who met the diagnostic criteria of the International Diabetes Federation, and 81 controls who applied to geriatrics and general internal medicine outpatient clinics for various reasons were included in the study.

The relationship between malnutrition and neutrophil-to-lymphocyte ratio in hospitalized older patient.

Objectives: Aging is characterized by appetite loss and cachexia, i.e., factors that contribute to malnutrition.

The impact of sarcopenia and obesity on mortality of older adults: five years results.

Aim: Sarcopenia and obesity can cause severe physical and metabolic complications. We aimed to investigate the risk of mortality associated with sarcopenia and obesity in older adults.

Method: We designed a retrospective, observational cohort study showing the 5-year mortality of older patients in a tertiary geriatric outpatient clinic.

Matrix Metalloproteinases/Tissue Inhibitors of Metalloproteinases Ratio: A Biomarker of Bone Resorption in Geriatric Osteoporosis?

Background: Matrix metalloproteinases (MMPs) play an important role in bone resorption and are regulated by tissue inhibitors of metalloproteinases (TIMPs). We investigated the use of MMP2/TIMP2 and MMP9/TIMP1 ratios as biomarkers of bone resorption in geriatric osteoporosis and evaluated the relationship between osteoporosis and geriatric syndromes.

Methods: This analytical cross-sectional study involved 87 patients (41 with osteoporosis) treated at the geriatric outpatient clinic of a university hospital.

Evaluation of malnutrition status and related risk factors in geriatric outpatient clinic.

Background/objectives: Malnutrition risk and malnutrition among the elderly is a public health concern. In combating this health-related problem, it is critically important to evaluate the risk factors in a multidimensional way and to apply appropriate nutrition intervention based on the results.

Subjects/methods: A cross-sectional study was conducted on 215 elderly patients (32.

Risk of sarcopenia in hospitalized patients and related clinical factors: a multicenter study from Turkey.

Purpose: To investigate the risk of sarcopenia in hospitalized older patients and to assess the associations between sarcopenia risk and health care outcomes including dependency, malnutrition, and dysphagia.

Methods: This multicenter cross-sectional study was a part of the annual National Prevalence Measurement of Quality of Care (LPZ) in Turkey. Hospitalized patients age 65 and older were included in the study.

Reliability and Validity of Rowland Universal Dementia Assessment Scale in Turkish Population.

Background: The aim is to validate Turkish version Rowland Universal Dementia Assessment Scale (RUDAS).

Methods: One hundred forty patients (>65 years) were included. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition -V was used in all patients.

[Nutrition in elderly patients with cardiovascular diseases].

Elderly population is rapidly increasing in Turkey as well as in the world. There are a number of factors that affect the nutritional status of elderly. Factors such as physiological changes that occur with aging, socioeconomic factors, dementia, depression, large number of chronic illnesses and excessive use of drugs, and low intake of food on the grounds of illness affect the feeding of elderly.

Prevalence of fecal incontinence and associated risk factors in elderly outpatients: a cross-sectional study.

Background: Data on the prevalence of fecal incontinence in elderly patients admitted to outpatient clinics in Turkey are scarce.

Aims: The aim of this study was to assess the prevalence of fecal incontinence and the associated risk factors in the elderly outpatients.

Methods: Patients 60 years and older admitted to a geriatrics outpatient clinic between October 2013 and March 2014 were included.

Biomarkers of lipid peroxidation related to hypertension in aging.

The aim of this clinical study was to evaluate the influence of aging on the levels of lipid peroxidation (quantified as thiobarbituric acid-reactive substances (TBARS) content), lipid hydroperoxide (LOOH), hexanoyl lysine (HEL), 8-iso-prostaglandin F2α (8-iso-PGF2α) and total antioxidant capacity (TAC), and determine their relationships to the demographic and cardiovascular risk factors in elderly hypertensive (HT) patients. This study consisted of four groups: two elderly groups with 30 HT patients (11 males, 19 females) and 30 normotensive healthy volunteers (15 males, 15 females), and two young groups with 30 HT patients (13 males, 17 females) and 30 normotensive healthy volunteers (12 males, 18 females). In the elderly control group, the TBARS, LOOH, HEL and 8-iso-PGF2α levels, and the carotid intima media thickness (CIMT) were significantly higher than in the young control group.

The role of protein oxidation and DNA damage in elderly hypertension.

Introduction: This study aimed to evaluate the role of protein oxidation and DNA damage in the elderly hypertensive (HT) patients.

Materials And Methods: This study consisted of four groups: two elderly groups with 30 HT patients and 30 normotensive healthy volunteers, and two young groups with 30 HT patients and 30 normotensive healthy volunteers. Plasma total thiol (T-SH), advanced oxidation protein products (AOPPs), protein carbonyl (PCO), ischemia modified albumin (IMA), urine 8-hydroxy-2'-deoxyguanosine (8-OHdG), and prooxidant-antioxidant balance (PAB) levels were measured.

Acromegaly and aging: a comparative cross-sectional study.

Objective: Cognitive and functional geriatric assessment may change in acromegaly. Herein we aimed to determine at which points geriatric assessment of the cases with acromegaly differs from that of general elderly population.

Design: In this comparative cross-sectional study, a total of 30 cases with acromegaly (controlled n = 14, uncontrolled n = 16) and 30 gender and body-mass index-matched cases without acromegaly (control group, CG) above 60 years old were included.

Prevalence and characteristics of restless legs syndrome (RLS) in the elderly and the relation of serum ferritin levels with disease severity: hospital-based study from Istanbul, Turkey.

The RLS is an underdiagnosed condition, characterized by unpleasant sensations in the legs. Pathophysiological mechanisms may include iron deficiency as reflected by low serum ferritin levels and dopaminergic system dysfunction. The purpose of our study was to investigate the prevalence and characteristics of RLS in the elderly and the relation of serum ferritin levels with disease severity.

Replicability and reliability of pain assessment forms in geriatrics.

Aim of the study was to investigate the replicability and reliability of the multi-dimensional health assessment questionnaire (MDHAQ) and visual analog scale (VAS) in young and elderly individuals with chronic pain. Ambulatory patients, 20 of them aged above 65 years and complaining about chronic pain and 20 patients with the age of 40 and younger working in a factory were assessed with VAS and MDHAQ. The assessment was repeated to investigate the replicability and reliability of both tests.

An unusual case of biliary obstruction caused by Dicrocoelium dentriticum.

Dicrocoelium dentriticum (D. dentriticum) is a liver fluke induced biliary obstruction. Infection usually occurs in herbivores such as sheep, goats and deer; human infection is very rarely encountered in clinical practice.

Depression and sex hormones in elderly women.

We aimed to study the relation between sex hormones and depression among elderly women. The study was carried out on 74 volunteered female subjects above 60 years of age. Each subject was asked to fulfill the geriatric depression scale (GDS) questionnaire and further evaluated for clinical depression by a psychiatrist using the DSM IV diagnostic criteria.

The effect of pulsed ultrasound exposure on the oxygen dissociation curve of human erythrocytes in in vitro conditions.

The P(50) value, a marker for the behavior of the oxygen dissociation curve (ODC) and values of 2,3-diphosphoglyceric acid (2,3-DPG), blood gases and acid base parameters (pH, PCO(2), actual HCO(3)(-), base excess, PO(2), SO(2)) and erythrocyte parameters (the number of erythrocyte, hematocrit and hemoglobin values) that are known to effect P(50), were measured before and after ultrasound (US) exposure to examine the effect of pulsed US beams on the ODC of human erythrocytes. Venous blood samples taken from healthy subjects were sonicated at 0 degrees C for 30 min by pulsed US beams with a constant frequency of 5 MHz. Experiments showed that the values of pH, actual HCO(3)(-), standard HCO(3)(-), base excess, 2,3-DPG and P(50) were changed considerably by pulsed US.