Publications by authors named "Denise S Schwartz"

Article Synopsis
  • Phantom limb pain (PLP) is common in amputees, and this study introduces a new tool, the PLP-PLS index, to differentiate between PLP and non-painful sensations (PLS).
  • The research analyzed data from 112 participants, using various regression models to identify how demographic and clinical factors relate to the PLP-PLS index.
  • Significant associations were found between phantom movement sensations and time since amputation with the PLP-PLS index, suggesting the need for further exploration into the different causes and treatment approaches for PLP and PLS.
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Article Synopsis
  • A study analyzed noncardiovascular and overall mortality rates in healthy cats and those with preclinical hypertrophic cardiomyopathy (pHCM), involving 1,730 cats across 21 countries.
  • The research found that while noncardiovascular death rates were similar between healthy cats and those with pHCM, overall mortality was significantly higher in pHCM cats due to increased cardiovascular issues.
  • Key causes of noncardiovascular death were cancer and chronic kidney disease, with age being a critical factor in mortality for both groups.
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Article Synopsis
  • - Hypertrophic cardiomyopathy (HCM) is the most common heart disorder in cats, causing significant health issues, but the effects of preclinical stages are not well understood.
  • - A study followed 1,730 cats, comparing those with nonobstructive HCM, obstructive HOCM, and healthy cats, revealing a high incidence of congestive heart failure (CHF) and cardiovascular death over time.
  • - Results showed that preclinical HCM/HOCM significantly increases the risks of CHF, arterial thromboembolism, and cardiovascular death, highlighting the need for better monitoring and treatment options for affected cats.
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Background: Cardiac output (CO) is an important haemodynamic parameter to monitor in patients during surgery. However, the majority of the techniques for measuring CO have a limited application in veterinary practice due to their invasive approach and associated complexity and risks. Transoesophageal echocardiography (TEE) is a technique used to monitor cardiac function in human patients during surgical procedures and allows CO to be measured non-invasively.

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Human diabetic patients may have increased lactate levels compared to non-diabetics. Despite the use of lactate levels in critical care assessment, information is lacking for diabetic dogs. Therefore, this prospective cross-sectional clinical study aimed to determine lactate concentrations in 75 diabetic dogs [25 newly diagnosed non-ketotic diabetics, 25 under insulin treatment, and 25 in diabetic ketoacidosis (DKA)], compared to 25 non-diabetic dogs.

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A survey of the experiences of owners of diabetic dogs was carried out by distributing questionnaires to veterinary clinics in São Paulo, Brazil. A total of 93 dog owners were surveyed over a 4 month period and descriptive statistical analysis, frequency distribution and correlations were performed. In most cases the clinical condition of the dogs had improved following treatment and owners were largely satisfied with veterinary intervention.

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Background: The protective effect of carvedilol on multiple organ damage induced by angiotensin II (Ang II) remains unclear. The aim of this study was to evaluate the protective effect of carvedilol on the heart, liver, and kidney in rats infused with Ang II.

Material/methods: Wistar rats were randomly distributed into three groups: control (no treatment), continuously infused with Ang II (150 etag/min for 72 hr), and treated with Ang II + carvedilol (90 mg/kg/d).

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Opioids may exert a protective effect against ventricular arrhythmias via a vagally mediated mechanism. This study evaluated the effects of the opioid remifentanil on arrhythmogenicity of epinephrine during halothane anesthesia. Eight dogs were assigned to 2 treatments in a randomized crossover design, with 1-week intervals between treatments.

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For many vector-borne organisms, dogs can be used as sentinels to estimate the risk of human infection. The objective of this study was to use dogs as sentinels for multiple vector-borne organisms in order to evaluate the potential for human infection with these agents in southeastern Brazil. Blood from 198 sick dogs with clinicopathological abnormalities consistent with tick-borne infections were selected at the São Paulo State University Veterinary Teaching Hospital in Botucatu and tested for DNA and/or antibodies against specific vector-borne pathogens.

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The purpose of this study was to determine the serological and molecular prevalence of Bartonella spp. infection in a sick dog population from Brazil. At the São Paulo State University Veterinary Teaching Hospital in Botucatu, 198 consecutive dogs with clinicopathological abnormalities consistent with tick-borne infections were sampled.

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Objective: To determine the feasibility for use of a 6-minute walk test (6-MWT) in dogs with congestive heart failure (CHF) and document that the distance walked in 6 minutes decreases when a dog has CHF.

Animals: 16 young mature male hound-crossbred dogs weighing between 25 and 37 kg.

Procedure: An unobstructed path (22.

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