60-minute application of S-Caine Peel prior to 1,064 nm long-pulsed Nd:YAG laser treatment of leg veins.

Background And Objectives: Advancements in laser treatment of leg veins necessitate concurrent investigations in topical anesthesia to minimize treatment-related pain. To evaluate the efficacy of the S-Caine Peel for providing topical anesthesia after a 60-minute application.

Study Design/patients And Methods: A randomized, double-blinded, placebo-controlled trial was performed in two centers.

Thirty-minute application of the S-Caine peel prior to nonablative laser treatment.

Background: Advancements in nonablative laser technology necessitate concurrent developments in topical anesthesia, as patients have reported varying degrees of discomfort during these procedures. Although topical anesthetics have proven efficacious, they possess inherent limitations related to ease of use.

Objective: To evaluate the efficacy of the S-Caine Peel (ZARS Inc.