Publications by authors named "Denise Fong Mei Leong"
Cell Stem Cell
August 2011
Article Synopsis
- Female mammals have a special situation where one of their X chromosomes gets turned off in a random way, leading to a mix of active and inactive Xs in their cells.
- In human female cells, the inactive X remains that way even when we try to turn them into stem cells, which is different from what happens in mice.
- Researchers found that when studying specific cells from Rett syndrome patients, all the cells had the same inactive X, and they discovered a method to change this through a special process that helps keep the cells healthy and useful for studying diseases.
