Effect of Compactin on the Mycotoxin Production and Expression of Related Biosynthetic and Regulatory Genes in Toxigenic .

Zearalenone (ZEN) and deoxynivalenol (DON) are mycotoxins produced by various species of fungi. They contaminate agricultural products and negatively influence human and animal health, thus representing a serious problem of the agricultural industry. Earlier we showed that compactin, a secondary metabolite of , is able to completely suppress the aflatoxin B1 biosynthesis by Using the strain FC-19 able to produce DON and ZEN, we demonstrated that compactin also significantly suppressed both DON (99.