Plasmonic Nanosensor Array for Multiplexed DNA-based Pathogen Detection.

In this research we introduce a plasmonic nanoparticle based optical biosensor for monitoring of molecular binding events. The sensor utilizes spotted gold nanoparticle arrays as sensing platform. The nanoparticle spots are functionalized with capture DNA sequences complementary to the analyte (target) DNA.

Overcoming the refractivity limit in manufacturing environment.

We present a tracking interferometer with an intrinsic compensation of the refractive index of air. By using both wavelengths of a frequency doubled Nd:YAG laser the refractive index of air can be determined and compensated by the dispersion. One dimensional benchmark verification experiments in air conditioned and typical harsh, uncontrolled environment show an asymptotic length dependent uncertainty in the order of 0.