Publications by authors named "Denis Brouillette"
Background: While significant gains were made in the management of heart failure (HF), most patients are still diagnosed when they are acutely ill in hospital, often with advanced disease. Earlier diagnosis in the community could lead to improved outcomes. Whether a partnership and an educational program for primary care providers (PCP) increase HF awareness and management is unknown.
View Article and Find Full Text PDFBackground: In heart failure, specific target doses for each drug are recommended, but some patients receive suboptimal dosing, others are undertreated or remain chronically in a titration phase, despite having no apparent contraindication or intolerance. We assessed the association of different levels of adherence to guidelines with outcomes in patients with heart failure and reduced ejection fraction (HFrEF).
Methods: Medical records of patients with HFrEF followed at our heart failure (HF) clinic for at least 6 months (n = 511) were reviewed and patients categorized as: 1) optimized (25.
Article Synopsis
- The study aimed to create specific quality indicators for assessing how well community pharmacists manage oral anticoagulant treatments for patients with atrial fibrillation (AF).
- It consisted of three phases: generating potential indicators from guidelines, evaluating them with expert input for relevance and measurability, and testing feasibility in community pharmacies.
- The final set includes 38 indicators in six categories, focusing on various aspects of care, with a tool developed for pharmacists to evaluate their management of these medications.
Drug-induced thrombocytopenia is a rare but serious adverse event that has been associated with multiple drugs including β-lactams. Although it mostly occurs with prolonged medication use, some cases of rapid-onset thrombocytopenia have been reported. We describe the case of a 69-year-old man who developed severe and immediate thrombocytopenia following reexposure to piperacillin-tazobactam in the critical care setting.
View Article and Find Full Text PDFStudy Objective: To evaluate the impact of a pharmacist-led warfarin patient self-management program on quality of life and anticoagulation control compared with management in a physician-led specialized anticoagulation clinic.
Design: Prospective, randomized, controlled, open-label trial.
Setting: Tertiary care academic medical center.