Publications by authors named "Denis Bredov"
Article Synopsis
- During gastrulation and neurulation in vertebrate embryos, the chordamesoderm and neuroectoderm converge and extend under a genetic program.
- This study investigates whether mechanical tension from these movements influences gene expression in these tissues.
- By analyzing stretched midgastrula embryo explants, researchers found that mechanical stretching activates certain genes in the stretched trunk region while inhibiting others in low-stretch areas, suggesting that mechanical forces could regulate embryonic patterning and development.
The article is devoted to physical views on embryo development as a combination of structurally stable dynamics and symmetry-breaking events in the general process of self-organization. The first corresponds to the deterministic aspect of embryo development. The second type of processes is associated with sudden increase of variability in the periods of symmetry-breaking, which manifests unstable dynamics.
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