Publications by authors named "Denilce R Sumita"
Article Synopsis
- - A collaborative exercise involving multiple labs was conducted to evaluate how effectively different laboratories can analyze DNA from old bone samples, specifically those around 150 and 400 years old, supplied by institutions in Prague.
- - Eighteen participating laboratories used various techniques for DNA typing, and while they achieved consistent results for the 150-year-old sample, the 400-year-old sample presented challenges due to its degraded condition.
- - The study highlights the importance for labs to routinely check their methods for identifying degraded DNA in bone and teeth samples, ensuring minimal contamination risks during the process.
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci.
Forensic Sci Int Genet
September 2014
In a worldwide collaborative effort, 19,630 Y-chromosomes were sampled from 129 different populations in 51 countries. These chromosomes were typed for 23 short-tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385ab, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATAH4, DYS481, DYS533, DYS549, DYS570, DYS576, and DYS643) and using the PowerPlex Y23 System (PPY23, Promega Corporation, Madison, WI). Locus-specific allelic spectra of these markers were determined and a consistently high level of allelic diversity was observed.
View Article and Find Full Text PDFRandom X inactivation and extensive mosaicism in human placenta revealed by analysis of allele-specific gene expression along the X chromosome.
PLoS One
June 2010
Imprinted inactivation of the paternal X chromosome in marsupials is the primordial mechanism of dosage compensation for X-linked genes between females and males in Therians. In Eutherian mammals, X chromosome inactivation (XCI) evolved into a random process in cells from the embryo proper, where either the maternal or paternal X can be inactivated. However, species like mouse and bovine maintained imprinted XCI exclusively in extraembryonic tissues.
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