Development of a prognostic gene signature and exploration of P4HA1 in the modulation of cuproptosis in colorectal cancer.

Cuproptosis, a newly identified form of cell death, has drawn increasing attention for its association with various cancers, though its specific role in colorectal cancer (CRC) remains unclear. In this study, transcriptomic and clinical data from CRC patients available in the TCGA database were analyzed to investigate the impact of cuproptosis. Differentially expressed genes linked to cuproptosis were identified using Weighted Gene Co-Expression Network Analysis (WGCNA).

An adaptive group sparse feature decomposition method in frequency domain for rolling bearing fault diagnosis.

Group-sparse mode decomposition (GSMD) is a decomposition method designed based on the group sparse property of signals in frequency domain. It is proved to be highly efficient and robust against noise, showing bright prospects for bearing fault diagnosis. However, the following adverse factors may impede its application for incipient bearing fault feature extraction: Initially, the GSMD method did not consider the impulsiveness and periodicity of the bearing fault feature.

Stabilization and Mineralization Mechanism of Cd with Cu-Loaded Attapulgite Stabilizer Assisted with Microwave Irradiation.

Cadmium (Cd) in soil was stabilized using copper loaded attapulgite (Cu/ATP) in a microwave (MW) system. Excellent Cd stability in soil was achieved with Cu/ATP addition due to higher adsorption energy (1.38 eV) of Cu/ATP for Cd than that of ATP (∼1 eV), confirmed by density functional theory calculations.