Publications by authors named "Deng-Xuan Mao"
[Preparation of two tanshinone Ⅱ_A-astragaloside Ⅳ co-loaded nano-delivery systems and in vitro antitumor activity comparison].
Zhongguo Zhong Yao Za Zhi
February 2023
Article Synopsis
- This study focused on developing effective nano-drug delivery systems for two antitumor compounds, tanshinone Ⅱ_A (TSA) and astragaloside Ⅳ (As), using microemulsions (TSA-As-MEs) and metal-organic frameworks (MOF).
- Two preparation methods were used: microemulsions through water titration and MOF via a hydrothermal method, with various characterization methods like DLS, TEM, and SEM employed to assess their properties.
- Results showed that while TSA-As-MEs had a smaller particle size and lower drug loading efficiency (0.22%), the TSA-As-MOF system demonstrated superior drug loading (15.35%) and greater effectiveness in inhib