Publications by authors named "Deng Wang"

Background: Physical activity interventions positively influence executive functions in both the general population and individuals with ADHD. However, there is limited research focusing on school-aged children, who have the highest ADHD diagnosis rates. This study aims to provide targeted intervention strategies for improving executive function in this population, offering a practical reference for selecting specific exercise types when designing interventions for children with ADHD.

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Although fossil evidence suggests the existence of an early muscular system in the ancient cnidarian jellyfish from the early Cambrian Kuanchuanpu biota (ca. 535 Ma), south China, the mechanisms underlying the feeding and respiration of the early jellyfish are conjectural. Recently, the polyp inside the periderm of olivooids was demonstrated to be a calyx-like structure, most likely bearing short tentacles and bundles of coronal muscles at the edge of the calyx, thus presumably contributing to feeding and respiration.

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Most firms will experience a decline in their development process. The contraction in demand and the impact of COVID-19 have exacerbated a firm's performance. Under the dilemma of resources reduction and recovery, the declining firm pays more attention to the efficient utilization of the diminishing innovation resources.

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Fullerene derivatives are widely employed as efficient electron-transporting layers (ETLs) in p-i-n perovskite photovoltaics but face challenges in mitigating interfacial recombination losses and ensuring stable film morphology. Non-fullerene acceptors (NFAs), commonly utilized in organic photovoltaics, present a promising alternative to fullerene-based ETLs. Nevertheless, the suboptimal performance of NFA-based devices underscores the need for molecular engineering to tailor their properties.

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Serotonin (5-HT) is a neurotransmitter that has been linked to tumorigenesis. Whether and how 5-HT modulates cells in the microenvironment to regulate tumor metastasis remains to be largely unknown. Here, we demonstrate that 5-HT is secreted by neuroendocrine prostate cancer (NEPC) cells to communicate with neutrophils and to induce neutrophil extracellular traps (NETs) in the liver, which in turn facilitates the recruitment of disseminated cancer cells and promotes liver metastasis.

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Ecdysozoan worms (Nematoida + Scalidophora) are typified by disparate grades of neural organization reflecting a complex evolutionary history. The fossil record offers a unique opportunity to reconstruct the early character evolution of the nervous system via the exceptional preservation of extinct representatives. We focus on their nervous system as it appears in early and mid-Cambrian fossils.

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Chemically modifiable small-molecule hole transport materials (HTMs) hold promise for achieving efficient and scalable perovskite solar cells (PSCs). Compared to emerging self-assembled monolayers, small-molecule HTMs are more reliable in terms of large-area deposition and long-term operational stability. However, current small-molecule HTMs in inverted PSCs lack efficient molecular designs that balance both the charge transport capability and interface compatibility, resulting in a long-standing stagnation of power conversion efficiency (PCE) below 24.

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In mammals, temporal and spatial variation in appendage sizes within and among species may be driven by variations in ambient temperature and allometric scaling. Here, we use two decades of morphological data on three rodent species distributed across vast latitudinal gradients in China to estimate temporal and spatial trends of tail, hind-foot, and ear lengths. Further, we test 14 climate variables to identify the critical drivers of these trends and use structural equation modeling (SEM) to analyze whether the effects of climate variables on the appendage lengths are direct or indirect, via effects on body length.

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Purpose: Considering the low survival rate for the numerous hip-preserving procedures developed for treating early-stage osteonecrosis of the femoral head (ONFH), this study aimed to evaluate short-term clinical outcomes following avascular necrosis (AVN) CAGE implantation.

Methods: 58 hips with early-stage ONFH (44 with Association Research Circulation Osseous [ARCO] stage 2 and 14 with stage 3A) treated with the AVN CAGE between August 2018 and December 2021 were included. The survival rates were analysed using radiographic progression and conversion to subsequent total hip arthroplasty (THA) as endpoints.

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Acute lung injury (ALI) is a devastating clinical syndrome without effective therapy. Celastrol, as a natural anti-inflammatory compound, has showed therapeutic potential against inflammatory diseases. In this study, we have investigated the potential effect of Celastrol on lipopolysaccharide (LPS)-induced ALI.

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Article Synopsis
  • Hybrid tin-lead (Sn-Pb) perovskites are important for improving the efficiency of tandem solar cells but face challenges like Sn oxidation and fast crystallization that hurt their performance.
  • Researchers introduced an additive called 2-amino-3-mercaptopropanoic acid hydrochloride (AMPH), which helps stabilize Sn during film preparation and slows down crystallization, resulting in higher-quality films.
  • With AMPH, single-junction perovskite solar cells achieved a power conversion efficiency of 23.07%, and tandem cells reached a certified efficiency of 27.83%, maintaining over 85% efficiency after 500 hours of use.
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  • Iron-loaded cancer-associated fibroblasts (FerroCAFs) contribute to immunosuppression in prostate cancer and are linked to negative clinical outcomes.
  • FerroCAFs secrete proteins that recruit immunosuppressive myeloid cells and are found in various cancers, identified by a common cell surface marker.
  • Inhibiting the Hmox1/iron/Kdm6b signaling pathway in FerroCAFs can enhance anti-tumor immunity and offers potential targets for cancer therapy.
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  • The rise in use of second-generation anticoagulant rodenticides (SGARs) has sparked concerns about their safety for non-target animals and environmental effects.
  • Research has identified specific mutations in the Vkorc1 gene that lead to anticoagulant resistance in Norway rats, particularly noting three mutations (A26T, C96Y, A140T) found in rat populations across China.
  • Understanding these mutations and their origins can help in developing more effective rodent control strategies, emphasizing the need to adopt less toxic first-generation anticoagulant rodenticides (FGARs) in susceptible areas.
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Coronary heart disease is a prevalent cardiovascular ailment globally, with myocardial infarction (MI) being one of its most severe manifestations. The morbidity and mortality of MI are escalating, showing an increasing trend among younger, highly educated individuals, thereby posing a serious threat to public health. Currently, thrombolysis, percutaneous coronary intervention, and coronary artery bypass grafting are the primary clinical treatments for MI.

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  • Interfacial management in perovskite solar cells (PSCs) is a major challenge, particularly in improving efficiency and stability by addressing carrier transport barriers and reducing non-radiative recombination.
  • The study explores the use of fluorine-terminated dual-site organic dipole molecules to create a tunable interfacial field, utilizing both experimental and theoretical approaches.
  • The findings demonstrate that these dipole molecules enhance energy level alignment at the perovskite interface, achieving a remarkable efficiency of 25.47% and improved stability under prolonged illumination, contributing valuable insights for advancing perovskite-based optoelectronic devices.
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High Epidermal growth factor receptor (EGFR) in Cutaneous Squamous Cell Carcinoma (cSCC) is associated with poor prognosis and advanced metastatic stages, severely impeding the efficacy of EGFR-targeting immunotherapy. This is commonly attributed to the combinatory outcomes of hypoxic tumor microenvironment (TME) and immunosuppressive effector cells together. Herein, a novel paradigm of EGFR-targeting oxygen-saturated nanophotosensitizers, designated as CHPFN-O, has been specifically tailored to mitigate tumor hypoxia in EGFR-positive cSCC and achieve Cetuximab (CTX)-mediated immunotherapy (CIT).

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  • Amomum villosum Lour. is a highly regarded medicinal plant with documented uses since the Tang Dynasty, primarily for its fruit, which is valued for both medicinal and culinary purposes.
  • The review focuses on the comprehensive analysis of A. villosum's distribution, botany, traditional uses, phytochemistry, pharmacological effects, quality control, clinical applications, and toxicity.
  • Approximately 500 bioactive compounds have been isolated from A. villosum, demonstrating diverse pharmacological activities like anti-inflammatory, antioxidant, anti-tumor, and antimicrobial effects.
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  • Researchers developed a new self-assembled multilayer (SAMUL) for hole-extraction in inverted perovskite solar cells, differing from traditional monolayers and disordered bilayers.
  • The SAMULs enhance PSC performance and stability by improving surface coverage and are optimized through variations in molecular structure and deposition methods like thermal evaporation and spin-coating.
  • The CbzNaphPPA SAMUL demonstrated exceptional crystallinity and hole mobility, achieving a power conversion efficiency of 26.07% and maintaining 94% of its initial efficiency after 1200 hours of continuous operation at high temperatures.
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  • Researchers describe a newly identified tiny ecdysozoan from the Cambrian period, characterized by its unique sack-like shape and spiny features.
  • This organism challenges the idea that early ecdysozoans always had a worm-like body plan, suggesting they may not have been elongated and tubular like many modern relatives.
  • The study positions this new species as a close relative to all known ecdysozoans, offering important insights into the evolutionary history and characteristics of early animal forms.
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Lobopodians represent a key step in the early history of ecdysozoans since they were the first animals to evolve legs within this clade. Their Cambrian representatives share a similar body plan with a typically cylindrical annulated trunk and a series of non-jointed legs. However, they do not form a monophyletic group and likely include ancestors of the three extant panarthropod lineages (Tardigrada, Onychophora, Euarthropoda).

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Flexible sensors have developed rapidly due to their great application potential in the intelligent era. However, the frequent bending work requirements pose a serious challenge to the mechanical reliability of flexible sensors. Herein, a strategy of using a new multielectrode layout to achieve multiple sensing signals based on one external signal is proposed for the first time to improve the reliability of flexible piezoresistive sensors.

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Carbon-based inorganic CsPbIBr perovskite solar cells (C-IPSC) have attracted widespread attention due to their low cost and excellent thermal stability. Unfortunately, due to the soft ion crystal nature of perovskite, inherent bulk defects and energy level mismatch at the CsPbIBr/carbon interface limit the performance of the device. In this study, we introduced aromatic benzyltrimethylammonium chloride (BTACl) as a passivation layer to passivate the surface and grain boundaries of the CsPbIBr film.

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  • * Analysis showed that nabothian cyst prevalence decreased as NAD levels increased, with the highest prevalence observed in the lowest NAD quartile.
  • * Specifically, participants in the lowest NAD quartile had a significantly higher adjusted odds ratio for having total nabothian cysts compared to those with the highest NAD levels, indicating that higher NAD levels may reduce the risk of these cysts.
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Adherence is key for achieving the optimal benefits from a weight loss intervention. Despite the number of studies on factors that promote adherence, their findings suggest inconsistent and fragmented evidence. The aim of this study was to review the existing factors of adherence to weight loss interventions and to find factors that facilitate the design of effective intervention programs.

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Cell plasticity has been found to play a critical role in tumor progression and therapy resistance. However, our understanding of the characteristics and markers of plastic cellular states during cancer cell lineage transition remains limited. In this study, multi-omics analyses show that prostate cancer cells undergo an intermediate state marked by Zeb1 expression with epithelial-mesenchymal transition (EMT), stemness, and neuroendocrine features during the development of neuroendocrine prostate cancer (NEPC).

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