Corticosteroids in Sepsis and Septic Shock: A Systematic Review, Pairwise, and Dose-Response Meta-Analysis.

Objectives: To perform a systematic review and meta-analysis to assess the efficacy and safety of corticosteroids in patients with sepsis.

Data Sources: We searched PubMed, Embase, and the Cochrane Library, up to January 10, 2023.

Study Selection: We included randomized controlled trials (RCTs) comparing corticosteroids with placebo or standard care with sepsis.