Quantitation and localisation of aluminum in human cancellous bone in renal osteodystrophy.

There is increasing evidence that aluminium toxicity may be responsible for a type of vitamin D-resistant osteomalacia and an unusually severe form of dementia ("dialysis dementia") occurring in some patients with chronic renal failure on regular haemodialysis. High concentrations of Al have been found in blood, bone and brain tissue from these patients. The A1 comes either from the water used during dialysis (added in some public water supplies during purification to precipitate contaminants) or from aluminium salts taken orally to bind phosphates and so restrict their dietary adsorption.

Aspects of microprobe analysis of mineralized tissues.

Mineralizing tissues were the first biological specimens to be examined by the electron microprobe. The necessity for performing analyses at high spatial resolution has led to the increasing use of energy dispersive (ED) detectors in CTEMs/STEMs. Because the ED detector accepts x-rays from a large solid angle, it often detects a large extraneous x-ray contribution from the instrument.

Effect of hexoestrol on the response of finishing steers to treatment with trenbolone acetate.

The relative effectiveness of implanting 300 mg trenbolone acetate alone or in combination with either 15, 30 or 45 mg hexoestrol was studied in three 90-day experiments using 64 Friesian steers. In experiment 1 hexoestrol was shown to improve live-weight gain and efficiency of feed conversion in steers implanted with trenbolone acetate. In experiments 2 and 3 trenbolone acetate in combination with 30 mg hexoestrol gave a better growth response than when combined with either 15 or 45 mg.