Medical comorbidities should not deter the application of laparoscopic fundoplication.

Introduction: Laparoscopic Nissen fundoplication offers significant improvement in gastroesophageal reflux disease (GERD) symptom severity and frequency. This study was undertaken to determine the impact of preoperative medical comorbidities on the outcome and satisfaction of patients undergoing fundoplication for GERD.

Methods: Prior to fundoplication, patients underwent esophageal motility testing and 24-h pH monitoring.