Knowledge mapping of planetary boundaries based on bibliometrics analysis.

The planetary boundaries concept has triggered a vast amount of pure and applied scientific research, as well as policy and governance activities globally. Indeed, it has rapidly become a centerpiece of sustainability study. It is crucial to review the scientific state of the planetary boundaries (PB) concept systematically.

Circular RNA LONP2 regulates proliferation, invasion, and apoptosis of bladder cancer cells by sponging microRNA-584-5p.

Bladder cancer (BC) is the most frequent type of urinary tumor and a barely treatable disease. Although extensive efforts have been invested in the research of BC, the underlying etiology and pathophysiology remain unclear. CircLONP2 is a circular RNA implicated in the development of many cancers, and miR-584-5p and YAP1 have been reported to contribute to the progression of BC.

A novel and injectable strontium-containing hydroxyapatite bone cement for bone substitution: A systematic evaluation.

Reconstruction of bone defects is still a challenge. In this study, we developed and systematically evaluated a novel injectable strontium-containing hydroxyapatite (Sr-HA) bone cement in which Sr-HA powder included 5% Sr and was mixed with a setting liquid that included 5% potassium citrate. This Sr-HA cement was mainly composed of HA and α-tricalcium phosphate (TCP) and exhibited favorable injectability (100%), setting times (the initial setting time was 240 s and the final setting time was 420 s), compressive strength (73.

[Analysis of Gene Mutation Types of Thalassemia in Yulin Childbearing-age Population of Guangxi China].

Objective: To investigate the genotype distribution of thalassemia in the population of childbearing age in Yulin area.

Methods: The polymerase reaction (PCR) combined with agargel eletrophoresis and reserve dot bolt hybridization was used to detected the α- and β-thalassemia gene in 31 769 cases of suspected thalassemia population at childbearing-age.

Results: A total of 22 254 cases were identified as thalassemia gene detetion or mutation in 31 769 cases with a detecting rate of 70.

The involvement of FBP1 in prostate cancer cell epithelial mesenchymal transition, invasion and metastasis by regulating the MAPK signaling pathway.

Prostate cancer (PCa) is a frequently occurring malignancy in males, and epithelial mesenchymal transition (EMT) plays a critical role in PCa metastasis. Thus, developing biomarkers inhibiting EMT may provide significance for treatment of PCa. Hence, the aim of the current study was to investigate the mechanism by which FBP1 gene silencing influences PCa cell EMT, invasion and metastasis by mediating the MAPK pathway.

Complete and Rapid Conversion of Hydrazine Monohydrate to Hydrogen over Supported Ni-Pt Nanoparticles on Mesoporous Ceria for Chemical Hydrogen Storage.

The development of active, selective, and robust catalysts is a key issue in promoting the practical application of hydrazine monohydrate (N2 H4 ⋅H2 O) as a viable hydrogen carrier. Herein, the synthesis of a supported Ni-Pt bimetallic nanocatalyst on mesoporous ceria by a one-pot evaporation-induced self-assembly method is reported. The catalyst exhibits exceptionally high catalytic activity, 100 % selectivity, and satisfactory stability in promoting H2 generation from an alkaline solution of N2 H4 ⋅H2 O at moderate temperatures.

[Fabrication and physical properties of porous individual beta-TCP scaffold to reconstruct residual alveolar ridge in dog].

Purpose: To fabricate porous individual beta-tricalcium phosphate scaffold and test its properties in dog.

Methods: A model of residual alveolar ridge in mandible of a dog was made and CT scanned after 3 months.The data of CT was transformed to 3-D format by MIMICS 7.

Effects of SWNT and metallic catalyst on hydrogen absorption/desorption performance of MgH2.

The microstructure and absorption/desorption characteristics of composite MgH2 and 5 wt % as-prepared single-walled carbon nanotubes (MgH2-5ap) obtained by the mechanical grinding method were investigated. Experimental results show that the MgH2-5ap sample exhibits faster absorption kinetics and relatively lower desorption temperature than pure MgH2 or MgH2-purified single-walled carbon nanotube composite. Storage capacities of 6.

[In vitro study on the cytotoxicity of strontium substituted hydroxyapatite].

Objective: To evaluate the cytotoxicity of strontium substituted hydroxyapatite.

Methods: Cell Relative Growth Rate(RGR) method, MTT assay and Flow Cytometry(FCM) method were used, and the strontium substituted hydroxyapatite contained different strontium concentration(0%,1%,5%,10%,100%).

Results: It was found that there's no apparent cytotoxicity of all the strontium substituted hydroxyapatite,but the cytotoxicity increased as the strontium concentration raised.