Publications by authors named "Demian Ifeanyi Njoku"
Microfluidic Paper-based Analytical Devices (µPADs) have emerged as a new class of microfluidic systems, offering numerous advantages over traditional microfluidic chips. These advantages include simplicity, cost-effectiveness, stability, storability, disposability, and portability. As a result, various designs for different types of assays are developed and investigated.
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- Using responsive nanoplatforms to deliver photosensitizers can tackle issues in photodynamic therapy (PDT) like solubility and toxicity.
- This strategy involves transforming nanoparticles into nanofibers through the action of specific enzymes, enhancing their effectiveness in generating reactive oxygen species (ROS) in cancer cells.
- The approach also allows for targeted delivery to mitochondria using the enzyme sirtuin 5, leading to improved mitochondrial function and greater anticancer results in PDT.