Psychometric properties of the Specific Thalassemia Quality of Life Instrument for adults.

Background: No specific questionnaire has been developed to assess the health-related quality of life of thalassemia patients. Thus, the main objective of this study was to develop, according to psychometric standards, a self-administered Specific Thalassemia Quality of Life Instrument (STQOLI) for adult patients.

Methods: First, a qualitative phase was conducted to generate items and identify domains using the critical analysis incident technique and a literature review.