Publications by authors named "Demel A"

Article Synopsis
  • Preterm lambs were studied to evaluate the effects of different levels of continuous positive airway pressure (CPAP) on pulmonary blood flow (PBF), cerebral blood flow (CBF), and jugular vein pressure (JVP) after birth.
  • Lambs were assigned to receive low-CPAP (5 cmHO), high-CPAP (15 cmHO), or dynamic high-CPAP (decreasing from 15 to 8 cmHO) for up to 30 minutes.
  • Results showed that high-CPAP significantly increased PBF without negatively impacting CBF and JVP, suggesting it can safely support preterm infants without adverse cardiovascular effects.
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Aim: This pilot study evaluated changes in regional cerebral oxygen saturation and cerebral blood flow volume during the transitional period in healthy term and moderately preterm infants.

Methods: The cohort comprised 16 preterm infants and seven full-term infants with mean gestational ages of 34 and 39 weeks, respectively. Longitudinal measurements were conducted during the first three days after birth.

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Background: Brain-water content (BWC) decreases with maturation of the brain and potentially affects parameters of cerebral oxygenation determined by near-infrared spectroscopy (NIRS). Most commercially available devices do not take these maturational changes into account. The aim of this study was to determine the effect of different assumptions for BWC on parameters of cerebral oxygenation in preterm infants.

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Aim: We investigated the associations between staff work characteristics, parents' experiences and a number of medical outcome measures.

Methods: This explorative multicentre study took place in the neonatal intensive care units (NICUs) of five German university hospitals between 2009 and 2011. We assessed staff work characteristics by surveying 126 NICU nurses and 57 physicians and asked 214 parents about their relationships with staff.

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Near-infrared spectroscopy (NIRS) is increasingly used in neonatal intensive care. We investigated the impact of skin, bone, and cerebrospinal fluid (CSF) layer thickness in term and preterm infants on absorption-(μa) and/or reduced scattering coefficients (μs') measured by multidistance frequency-domain (FD)-NIRS. Transcranial ultrasound was performed to measure the layer thicknesses.

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Background: The reliability of the rapid urease test has not been proven in patients with peptic ulcer bleeding. Some studies show bad diagnostic results with the rapid urease test for gastrointestinal bleeding.

Aims: To evaluate the efficacy of the rapid urease test in patients with bleeding gastric or duodenal ulcers.

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Background And Study Aims: Eradication of Helicobacter pylori infection can reduce the rebleeding rate of peptic ulcer bleeding in the long term. There are few data on the influence of H. pylori on the rebleeding rate in the acute phase of bleeding however.

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