Publications by authors named "Delyana P Vasileva"
Article Synopsis
- - The study investigated a diverse group of 95 enzymes from the N-terminal nucleophile hydrolase superfamily, focusing on their ability to hydrolyze synthetic polyamides like nylon.
- - About 40% of these enzymes demonstrated significant nylon hydrolase activity, comparable to the well-known enzyme NylC, without any clear link between their evolutionary relationships and their hydrolytic capabilities.
- - Researchers identified several enzymes with strong substrate selectivity, especially those that efficiently processed Nylon 6,6, and also analyzed the crystal structure of a specific hydrolase to better understand the factors affecting its activity and selectivity.
In eukaryotes, fine-scale maps of meiotic recombination events have greatly advanced our understanding of the factors that affect genomic variation patterns and evolution of traits. However, in bacteria that lack natural systems for sexual reproduction, unbiased characterization of recombination landscapes has remained challenging due to variable rates of genetic exchange and influence of natural selection. Here, to overcome these limitations and to gain a genome-wide view on recombination, we crossed Bacillus strains with different genetic distances using protoplast fusion.
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