Chemical and Biological Investigations of Antiviral Agents Against Plant Viruses Conducted in China in the 21st Century.

Research into the biology of plant viruses, their mechanisms of pathogenicity, and the induction of host resistance has laid a solid foundation for the discovery of antiviral agents and their targets and the development of effective control technologies. Additionally, recent advancements in fields such as chemical biology, cheminformatics, bioinformatics, and synthetic biology have provided valuable methods and tools for the design of antiviral drugs, the synthesis of drug molecules, assessment of their activity, and investigation of their modes of action. Compared with drug development for human viral diseases, the control of plant viral diseases presents greater challenges, including the cost-benefit of agents, simplification of control technologies, and the effectiveness of treatments.

The Microbial Metabolite Wuyiencin Potential Targets Threonine dehydratase in to Achieve Control of Tea Leaf Spot.

Tea leaf spot caused by is a disease that has recently been discovered in the tea plantations of Southwest China, and which has a significant negative impact on the yield and quality of tea leaves. Wuyiencin is a nucleotide antimicrobial that is effective against a range of fungal diseases. However, its mode of action is still unclear.

Phenazine-1-carboxamide Regulates Pyruvate Dehydrogenase of Phytopathogenic Fungi to Control Tea Leaf Spot Caused by .

Due to a lack of understanding of the disease epidemiology and comprehensive control measures, tea leaf spot caused by has a significant negative impact on tea yield and quality in the tea plantations of Southwest China. Phenazine-1-carboxamide (PCN) is a phenazine compound derived from species, which exhibits antimicrobial activity against various pathogens. However, its inhibitory mechanism is not yet clear.

Pyriofenone Interacts with the Major Facilitator Superfamily Transporter of Phytopathogenic Fungi to Potentially Control Tea Leaf Spot Caused by .

Tea leaf spot caused by is a newly discovered fungal disease in southwest China. Due to a lack of knowledge of its epidemiology and control strategies, the disease has a marked impact on tea yield and quality. Pyriofenone is a new fungicide belonging to the aryl phenyl ketone fungicide group, which has shown marked efficacy in controlling various fungal diseases.

The Past, Present, and Future of Plant Activators Targeting the Salicylic Acid Signaling Pathway.

Plant activators have emerged as promising alternatives to conventional crop protection chemicals for managing crop diseases due to their unique mode of action. By priming the plant's innate immune system, these compounds can induce disease resistance against a broad spectrum of pathogens without directly inhibiting their proliferation. Key advantages of plant activators include prolonged defense activity, lower effective dosages, and negligible risk of pathogen resistance development.

Response of blueberry photosynthetic physiology to light intensity during different stages of fruit development.

To investigate the response of blueberry photosynthetic physiology to different light intensities during different stages of fruit development. In this study, four light intensity treatments (25%, 50%, 75% and 100% of full light) were set up to study the change rule of photosynthetic pigment content and photosynthetic characteristics of 'O'Neal' southern highbush blueberry leaves during the white fruiting stage (S1), purple fruiting stage (S2) and blue fruiting stage (S3) under different light intensity environments, and to explore the light demand and light adaptability of blueberry during different developmental stages of the fruit. The results showed that the chlorophyll and carotenoid contents of blueberry leaves showed an increasing trend with decreasing light intensity at all three stages of fruit development.

In Addition to Damaging the Plasma Membrane, Phenolic Monoterpenoid Carvacrol Can Bind to the Minor Groove of DNA of Phytopathogenic Fungi to Potentially Control Tea Leaf Spot Caused by .

Carvacrol expresses a wide range of biological activities, but the studies of its mechanisms focused on bacteria, mainly involving the destruction of the plasma membrane. In this study, carvacrol exhibited strong activities against several phytopathogenic fungi and demonstrated a novel antifungal mechanism against . RNA sequencing indicated that many genes of hyphae were predominately induced by carvacrol, particularly those involved in replication and transcription.

Physiological response of anthocyanin synthesis to different light intensities in blueberry.

Fruit color is an important economic character of blueberry, determined by the amount of anthocyanin content. Anthocyanin synthesis within the blueberry fruits is significantly affected by light. To reveal the physiological response mechanism of anthocyanin synthesis in blueberry fruits in different light intensities, four light intensities (100% (CK), 75%, 50% and 25%) were set for the 'O'Neal' southern highbush blueberry as the experimental material in our study.

Mode of Action of Heat Shock Protein (HSP) Inhibitors against Viruses through Host HSP and Virus Interactions.

Misfolded proteins after stress-induced denaturation can regain their functions through correct re-folding with the aid of molecular chaperones. As a molecular chaperone, heat shock proteins (HSPs) can help client proteins fold correctly. During viral infection, HSPs are involved with replication, movement, assembly, disassembly, subcellular localization, and transport of the virus via the formation of macromolecular protein complexes, such as the viral replicase complex.

What really influences the development of renewable energy? A systematic review and meta-analysis.

Promoting renewable energy (RE) is one key strategy to increase energy security and mitigate global warming. What really influences the development of RE has aroused public attention worldwide. Numerous studies have identified and evaluated the critical influence factors (CIFs) for renewable energy development (RED); however, there seems to be no consensus among the previous studies on these CIFs and their importance level or influence direction.

Effects of nitrogen, phosphorus and potassium formula fertilization on the yield and berry quality of blueberry.

Through the application ratio of nitrogen (N), phosphorus (P) and potassium (K) in the field, L9 (33) orthogonal experimental design was used to study the effects of different N, P and K ratios on the yield and quality of blueberry fruit, aiming to optimize the amount of supplied fertilizers. The results showed that N, P and K fertilizer had different effects on fruit yield and quality, among which K fertilizer was the most important factor. Fertilization could significantly improve the yield and fruit quality of blueberry, and the average yield of fertilization treatment was 37.

Genetic Diversity Analysis and Core Germplasm Collection Construction of Based on Fruit Phenotype and SSR Data.

Many germplasm resources were collected from Guizhou Province, but the fruit morphological variation and genetic diversity of germplasm resources remain unclear. The genetic diversity of germplasms resources in Guizhou was studied based on fruit traits and simple sequence repeat (SSR) molecular markers to build a core collection. This paper aims to provide a scientific basis for the collection, management, development, and utilization of resources in Guizhou province.

First Report of Stagonosporopsis caricae Causing Chayote Leaf Spot in Guizhou Province, China.

At present, chayote (Sechium edule (Jacq.) Swartz) have been widely planted in Guizhou Province, southwestern China, and the cultivation area in Huishui county ranks first among all the counties or cities in Guizhou Province. Chayote leaf spot was firstly observed in Huishui County (25.

Metabolome and transcriptome profiling unveil the mechanisms of light-induced anthocyanin synthesis in rabbiteye blueberry (vaccinium ashei: Reade).

Background: Blueberry is one of the most important fruit crops worldwide. Anthocyanin is an important secondary metabolites that affects the appearance and nutritive quality of blueberries. However, few studies have focused on the molecular mechanism underlying anthocyanin accumulation induced by light intensity in blueberries.

Multi-Omics Analysis Reveals that the Antimicrobial Kasugamycin Potential Targets Nitrate Reductase in to Achieve Control of Tea Leaf Spot.

Because of the lack of effective disease management measures, tea leaf spot-caused by the fungal phytopathogen (syn. )-is an important foliar disease. The important and widely used agricultural antimicrobial kasugamycin (Ksg), produced by the Gram-positive bacterium , effects high levels of control against crop diseases.

Impact of spatial misallocation of electric power resources on economic efficiency and carbon emissions in China.

The relationship between resource misallocation and productivity has become a hot topic in recent years, but few studies examined the impact of spatial misallocation of electric power resources (SMEPRs) on economic efficiency and carbon emissions. Here, we constructed a calculation model of SMEPRs that can measure both the misallocation degree and direction and uncovered the spatiotemporal evolvement mechanism of SMEPRs. On this basis, we explored the impact of SMEPRs on regional economic efficiency and carbon emissions using panel data from 29 provinces in China from 1988 to 2017.

Exploring the dilemma and influencing factors of ecological transformation of resource-based cities in China: perspective on a tripartite evolutionary game.

The ecological transformation of the mineral resource-based cities (MRBCs) is the key to promoting the construction of ecological civilization and realizing the sustainable development of the social economy and society in China. Existing research ignores the influence of public participation on other subjects in the process of transformation, which is essential to solve the dilemma faced by the ecological transformation of MRBCs. In view of this, from the perspective of stakeholders, this study constructs a new evolutionary game model, which is jointly participated in by the government, enterprises, and social factors (SF) (including public, self-media, and non-governmental organizations).

The Sequence and Integrated Analysis of Competing Endogenous RNAs Originating from Tea Leaves Infected by the Pathogen of Tea Leaf Spot, .

Tea leaf spot, caused by , is an important disease which negatively affects the productivity and the quality of tea leaves. During infection by the pathogen, competing endogenous RNAs (ceRNAs) from tea leaves could contribute to achieving pathogenicity. In this study, circular RNAs (circRNAs) and long noncoding RNAs (lncRNAs), constituting ceRNAs, which share binding sites on microRNAs (miRNAs), and messenger RNAs (mRNAs) from infected and uninfected leaves of tea ( 'Fuding-dabaicha') were sequenced and analyzed, and the identity and expression levels of the target genes of miRNA-mRNA and miRNA-lncRNA/circRNA were predicted.

First Report of Epicoccum nigrum Causing Brown Leaf Spot in Tea in Guizhou Province, China.

Brown leaf spots were observed on tea [Camellia sinensis (L.) Kuntze] in Sinan County (27.74 °N, 108.