[Progressive degenerative myoclonic epilepsy. Systematized olivo-cerebellar lesions].

A 15 year-old North-African female showed typical symptoms and evolution of Progressive Myoclonus Epilepsy of the Unverricht type. Pathological examination failed to show either inclusion bodies or any other storage material. The only relevant findings included degenerative changes in the inferior olives and, to a lesser extent, in the cerebellar cortex.

[Plasmocytic meningitis in multiple myeloma. An anatomo-clinical observation].

A confusional state due to hypercalcemia led to the discovery of multiple myeloma in a 73 year old man. The recurrence of a confusional state, related to plasma cell meningitis called for hospitalization. Serum, urine and cerebrospinal fluid immunoelectrophoresis revealed monoclonal immunoglobulines of lambda light chains.

[Development of aphasic symptomatology with age. Discussion apropos of an anatomo-clinical case].

Clinical data suggesting that aphasic semeiology undergo some evolution with age are summarized. Three kinds of hypotheses may account for this evolution: (1) a possible evolution with age of the site and extent of ischaemic lesions: (2) an evolution according to age of brain functional organization for language; and (3) evolution with age of psychological and/or social aspects of individuals in whom aphasia occurs. These hypotheses are discussed in the light of a clinico-pathological case of Wernicke's aphasia with logorrheic jargon due to an infarct involving both anterior and posterior parts of the left cortical speech area.

[Progressive multifocal leukoencephalopathy. Clinical, CT scan and neuropathologic findings. Apropos of 4 cases].

Four cases of progressive multifocal leukoencephalopaty are reported, 3 of them with an ultrastructural study and 2 with a C.T. scan study.

[Striatonigral degeneration associated with olivopontocerebellar atrophy. Anatomo-clinical study of 3 cases. Nosologic discussion].

Results of a clinicopathologic study in 3 cases of nigrostriatal degeneration associated with olivopontocerebellar atrophy are reported. The clinical picture was primarily that of parkinsonism but associated disorders were atypical: sphincter and deglutition disorders, pyramidal signs and action myoclonia; paralysis of vertical gaze (with a deficit of convergence in 1 case) and a cerebellar syndrome in 2 cases; postural hypotension with an invariable pulse, amyotrophy of the hands and a paradoxical response to Dopa: worsening of akineto-hypertonic symptomatology and deglutition disorders in 1 case. Pathologic examination showed similar lesions in the 3 cases: atrophy with pigmentation of the putamen and changes in the substantia nigra, associated with evidence of olivopontocerebellar degeneration.

[Clinical and pathological study of a peculiar form of tuberculous meningitis: diagnostic and therapeutic problems (author's transl)].

The authors report a case of tuberculous meningitis in which multiple bacteriological samples were negative during the eleven months of the clinical course. There were no other visceral localizations. The fatal outcome was due to vascular lesions (multiple cerebral infarcts), and to CSF flow disorders.

Primary cerebral neuroblastoma in an adult man.

Survey of the literature reveals 10 cases of cerebral neuroblastoma in adults. An additional case, confirmed by electron microscopy, is reported here. The patient had a voluminous supratentorial calcified intraventricular tumor with clinical signs dating back more than two years.

[Vascular epilepsy: clinical, electroencephalographic, and computerized tomographic aspects (author's transl)].

The authors report 31 cases of "vascular epilepsy" among 280 cerebral strokes confirmed by cranial computerized tomography. A high incidence of ischemia (28 cases : 90%) is noted. Epileptic seizures are initial (14 cases) or sequellar (17 cases) manifestations of cerebral stroke.

[Cerebral neuroblastoma in the adult. Clinical and C.T. scan aspects (author's transl)].

The case of a thirty two years old patient with a frontal syndrome developing over the last three years is reported. CT scan showed a large calcified lesion, situated on the median line enhanced by iodine. The patient was operated.

[Status epilepticus and multiple sclerosis (author's transl)].

Status epilepticus was a complicating feature of the last bout before the fatal outcome in a patient with a 11 years history of multiple sclerosis. The fits were seen as clonic movements of the eyes in a lateral direction, lasting for 30 to 90 seconds and repeated every 5 minutes on average. Electroencephalographic recordings demonstrated periodic slow spikes on the right hemisphere, starting in the anterior region.