Publications by authors named "Delphine Vauterin"
Research suggests that respiratory and cardiovascular drugs can ameliorate the rate of lung function decline. To investigate the impact of respiratory and cardiovascular pharmacotherapy on lung function trajectories in the general population. Repeated spirometry was performed in the Rotterdam Study, a population-based cohort of adults aged ≥45 years.
View Article and Find Full Text PDFBackground: Assessing medication adherence is crucial in chronic obstructive pulmonary disease (COPD) management to prevent exacerbations. However, it is unclear whether this association between adherence and exacerbations is influenced by the adherence assessment methods or thresholds used. Electronic healthcare databases are valuable to study exacerbations and adherence in real life.
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- The study investigates the prevalence of potentially inappropriate prescribing (PIP) in older patients (65+) with atrial fibrillation (AF) who are on multiple medications.
- A systematic review of twelve studies found that only one reported an overall PIP prevalence of 65%, while a meta-analysis revealed a 35% prevalence of PIP for direct oral anticoagulants (DOACs), but with significant variability among studies.
- The research indicated no strong links between PIP of DOACs and serious health outcomes like mortality or hospital readmissions, but findings on major bleeding differed, showing some potential associations.
Article Synopsis
- - The 2023 Global Initiative for Chronic Obstructive Lung Disease emphasizes the need to assess medication adherence in COPD using healthcare databases, prompting a review of existing methods in the literature.
- - Researchers reviewed 160 studies on medication adherence, identifying various methods for measuring initiation, implementation, and persistence of COPD treatment, with a focus on how these assessments were reported.
- - Findings revealed a lack of consistency in adherence methods, sparking a call for improved transparency and better reporting of variables that could influence adherence evaluations.
Purpose: Poor adherence to non-vitamin K antagonist oral anticoagulants (NOACs) may raise thromboembolic risks in patients with atrial fibrillation (AF). However, the minimal adherence to maintain the protective effect of NOACs is currently unknown. Therefore, we investigated thresholds of NOAC adherence in association with thromboembolic and mortality risks.
View Article and Find Full Text PDFAim: Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly preferred over vitamin K antagonists (VKAs) in atrial fibrillation (AF) management. However, differences in oral anticoagulant (OAC) prescribing according to patient's age, sex and physician's specialty may be present. Therefore, incident and prevalent use of OACs, NOACs and VKAs, stratified by age, sex and prescriber, and factors associated with the choice of OAC were investigated.
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