Publications by authors named "Delphine Regnard"

Introduction: Bronchiolitis is the leading cause of hospitalization for infants but its economic burden is not well documented. Our objective was to describe the clinical evolution and to assess the 1-month cost of a first episode of acute bronchiolitis presenting to the emergency department (ED).

Methods: Our study was an epidemiologic analysis and a cost study of the cohort drawn from the clinical trial GUERANDE, conducted in 24 French pediatric EDs.

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Article Synopsis
  • Acute bronchiolitis is a major reason for hospitalizations in infants, and previous research suggested limited effectiveness of nebulized hypertonic saline (HS) treatment in emergency settings.
  • The GUERANDE study was a large, multicenter clinical trial that aimed to determine if nebulized HS could reduce hospital admissions for infants experiencing their first acute bronchiolitis episode.
  • Results showed no significant difference in hospital admission rates between the HS group (48.1% admitted) and the normal saline (NS) group (52.2% admitted), although the HS group did show greater improvement in respiratory distress symptom scores.
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Objectives: The aim was to describe the epidemiological characteristics of childhood IgA vasculitis (IgAV) defined by the EULAR/PRINTO/Paediatric Rheumatology European Society criteria in a population-based sample from France and ascertain its incidence over 3 years by a four-source capture-recapture analysis.

Methods: Cases were prospectively collected in Val de Marne county, a suburb of Paris, with 263 874 residents <15 years old. Children with incident IgAV living in this area from 2012 to 2014 were identified by four sources of case notification (emergency departments, paediatrics departments, private-practice paediatricians and general practitioners).

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Emergency department (ED) visits for asthma exacerbation have not become less frequent, essentially because the self-management of mild-to-moderate asthma exacerbations by children and their families remains sub-optimal. The objective of our study was to assess the proportion of visits to EDs for asthma exacerbation that were potentially avoidable and their risk factors [such as no Written Asthma Action Plan (WAAP)]. We conducted an 8-month multicenter study in 6 French pediatric EDs.

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