Evaluation of urine specific gravity as a predictor of hypotension during anaesthesia in healthy dogs premedicated with dexmedetomidine.

Objective: To investigate the relationship between urine specific gravity (USG) and the risk of arterial hypotension during general anaesthesia (GA) in healthy dogs premedicated with dexmedetomidine and methadone.

Study Design: Prospective clinical cohort study.

Animals: A total of 75 healthy client-owned dogs undergoing GA for elective tibial plateau levelling osteotomy.

Use of midazolam in combination with medetomidine for premedication in healthy dogs.

Objective: To assess the sedative effects, propofol sparing properties and impact on quality of induction and intubation of intravenous (IV) medetomidine and midazolam administered consecutively at different doses compared to medetomidine alone in healthy dogs for premedication.

Study Design: Prospective, randomized, blinded, clinical study.

Animals: A total of 40 adult healthy client owned dogs, weighing 18 ± 7 kg (mean ± standard deviation).