Early psychomotor therapy in very preterm infants does not improve Bayley-III scales at 2 years.

Aim: To assess the efficacy of post-hospital psychomotor therapy in the development of very preterm infants at nine and 24 months.

Methods: We conducted a randomised controlled study at Toulouse Children's Hospital between 2008 and 2014 among preterm infants aged under 30 weeks. All infants in both groups could benefitt from physiotherapy to prevent motor disorders.

The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions.

Pancreatic β-cell failure in type 2 diabetes mellitus (T2DM) is associated with impaired regulation of autophagy which controls β-cell development, function, and survival through clearance of misfolded proteins and damaged organelles. However, the mechanisms responsible for defective autophagy in T2DM β-cells remain unknown. Since recent studies identified circadian clock transcriptional repressor REV-ERBα as a novel regulator of autophagy in cancer, in this study we set out to test whether REV-ERBα-mediated inhibition of autophagy contributes to the β-cell failure in T2DM.

Trends in prevalence and characteristics of post-neonatal cerebral palsy cases: a European registry-based study.

The present paper aims to analyze trends over time in prevalence of cerebral palsy of post-neonatal origin, to investigate whether changes are similar according to severity and to describe the disability profile by etiology. Post-neonatal cases, birth years 1976 to 1998, were identified from the Surveillance of Cerebral Palsy in Europe collaboration (19 population-based registries). A recognized causal event occurring between 28 days and 24 months of age was considered to define the cases.

[Spiruline as a food supplement in case of infant malnutrition in Burkina-Faso].

Background: Spiruline, a microscopic algae with nutritious quality was put forward as food supplement to fight malnutrition in infant.

Population And Methods: To assess its effectiveness, a survey was carried out among children with malnutrition whose Z-score was <2 for their age, in the Koudougou province, Burkina-Faso. Within five centers, three groups were defined at randomization: group 1 with usual nutritional rehabilitation program, group 2 as above + 5 g x d(-1) of spiruline, group 3 as above + spiruline + fish.