Publications by authors named "Dellavalle R"

Article Synopsis
  • The Global Burden of Disease (GBD) study focuses on understanding the worldwide prevalence and impact of significant diseases.
  • PatientsLikeMe (PLM) is an online platform where patients share their experiences, offering valuable insights into health conditions.
  • A comparison of data from GBD and PLM for dermatologic conditions showed both expected demographic differences and surprising correlations, suggesting that these data sources can work together to highlight unmet patient needs and priorities.
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To describe progression, content, and stringency of state legislation regulating indoor tanning and association with state government political party leadership. Trained research assistants used legal mapping methods to code legislative bills on indoor tanning introduced in US states, the District of Columbia, and Puerto Rico. We calculated composite scores on the stringency of age restrictions and of warnings, operator requirements, and enforcement.

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TikTok is a social media platform that can educate users about dermatology, but this longitudinal analysis of skin of color-related TikTok hashtags from 2021 to 2022 suggests that nondermatologist influencers continue to dominate content creation, highlighting the need for more participation from board-certified dermatologists to actively counter misinformation and address potential disparities in skin-of-color health care.

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Analyses of women dermatology literature authorship from 2018 to 2022 reveal a slight increase in total female authors, female first authors, and female senior authors with no substantial immediate impact of COVID-19 on current trends, encouraging future examination of long-term effects and ongoing promotion of systemic initiatives to support gender equity.

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Article Synopsis
  • This study examines how various social determinants of health (SDH), not just socioeconomic factors, impact the management of head-neck melanomas (HNM) in the U.S. using the Social Vulnerability Index (SVI).
  • It analyzed data from over 374,000 adults diagnosed with HNM from 1975 to 2017, revealing that higher social vulnerability is linked to reduced surgical options, increased likelihood of radiation treatment, and more advanced disease at diagnosis.
  • Key findings indicate that household composition, socioeconomic status, and minority-language status significantly influence disparities in HNM management, despite limitations like unknown causes of death and reliance on county-level SVI calculations.
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Article Synopsis
  • In 2023, JMIR Dermatology expanded its scope to include research on all aspects of skin, hair, and nail diseases, while acknowledging the contributions of reviewers, staff, and authors.
  • The journal introduced a new Research Letter format and an In Memorium article type to honor distinguished figures in the field of dermatology.
  • Additionally, the editorial highlights the top three publications from 2023 based on Altmetric scores and outlines future plans for the journal.
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Background: Pathogenesis of seborrheic dermatitis involves lipid secretion by sebaceous glands, Malassezia colonization, and an inflammatory response with skin barrier disruption. Each of these pathways could be modulated by diet, obesity, and nutritional supplements. Current treatment options provide only temporary control of the condition; thus, it is essential to recognize modifiable lifestyle factors that may play a role in determining disease severity.

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This paper demonstrates a new, promising method using generative artificial intelligence (AI) to augment the educational value of electronic textbooks and research papers (locally stored on user's machine) and maximize their potential for self-study, in a way that goes beyond the standard electronic search and indexing that is already available in all of these textbooks and files. The presented method runs fully locally on the user's machine, is generally affordable, and does not require high technical expertise to set up and customize with the user's own content.

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Article Synopsis
  • - The study assessed the number needed to biopsy (NNB) for melanoma in University of Colorado residency clinics, finding that the total NNB was 6.16, comparable to practicing dermatologists.
  • - Researchers analyzed data from 2016 to 2022, evaluating 2,230 biopsies with suspected melanoma, of which 362 were confirmed cases.
  • - The study examined the effects of the COVID-19 pandemic on NNB, revealing an increase from 5.86 pre-COVID to 6.91 post-COVID, though the change was not statistically significant.
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Online patient-oriented platforms such as PatientsLikeMe (PLM) offer a venue for individuals with various diagnoses to share experiences and build community, though they may not be representative of the larger patient population. This potentially limits generalizability and raises concerns about the spread of misinformation, emphasizing the need for informed use and health care provider engagement.

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Article Synopsis
  • - The study highlights that women continue to be underrepresented in leadership roles within academic dermatology, particularly on editorial boards of leading journals
  • - It stresses the importance of addressing this imbalance to enhance diversity, equity, and inclusion in the field
  • - The research calls for the development and implementation of proactive strategies to improve gender representation in these influential positions
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This research letter assesses male skin care content on social media in order to bring to light the lack of content regarding skin cancer prevention posted on Instagram for male audiences.

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  • Seborrheic dermatitis (SD) is common in people with Parkinson's disease (PD), affecting 18.6%-59%, and oral cannabidiol (CBD) may help reduce both sebum production and PD symptoms.
  • This study explores the potential benefits of CBD in decreasing the severity of SD in PD patients through a randomized, double-blind, placebo-controlled trial.
  • Results showed no significant treatment effect on SD severity between CBD and placebo groups, but there was a trend indicating improvement in the CBD group and worsening in the placebo group, suggesting further research is needed.
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Publications dealing with topics considered to be pertinent to diversity, equity, and inclusion are increasing. Due to the increasing trend, dermatology journals have started to implement ways to evaluate and understand these publications. Here, we discuss a keyword approach to identify and then categorize these publications.

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Actemra (tocilizumab) received emergency use authorization for the treatment of coronavirus disease 2019 (COVID-19) in June 2021. Literature has linked numerous cutaneous adverse effects to tocilizumab. In this current survey, investigators reviewed and compared these adverse effects to the common cutaneous manifestations of COVID-19.

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Article Synopsis
  • Atopic dermatitis (AD), or eczema, is a chronic skin condition characterized by severe itching, dryness, and redness, leading to a growing interest in alternative treatments away from traditional methods and costly biologics.
  • This review aimed to evaluate the effectiveness of oral nutritional supplements, probiotics, and vitamins on AD symptoms by analyzing studies from various medical databases published between 1993 and 2023.
  • Findings showed weak overall evidence for nutritional supplements in relieving AD symptoms, though specific probiotics like Lactiplantibacillus plantarum and Ligilactobacillus salivarius showed promise, highlighting the need for larger clinical trials to confirm their efficacy.
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Importance: Although several clinician- and patient-reported outcome measures have been developed for trials in hidradenitis suppurativa (HS), there is currently no consensus on which measures are best suited for use in clinical practice. Identifying validated and feasible measures applicable to the practice setting has the potential to optimize treatment strategies and generate generalizable evidence that may inform treatment guidelines.

Objective: To establish consensus on a core set of clinician- and patient-reported outcome measures recommended for use in clinical practice and to establish the appropriate interval within which these measures should be applied.

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Background: Atopic dermatitis (AD) is a common inflammatory disease caused by a type 2 T helper cell-mediated immune response to environmental antigens. Approximately 1 in 5 patients with AD presents with moderate to severe disease, and treatments approved by the Food and Drug Administration include emollients, topical glucocorticoids, and calcineurin inhibitors. Dupilumab, a fully human monoclonal antibody, improves AD via inhibition of interleukin-4 and interleukin-13.

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