Incidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics.

Trial enrichment using gut microbiota derived biomarkers by high-risk individuals can improve the feasibility of randomized controlled trials for prevention of Clostridioides difficile infection (CDI). Here, we report in a prospective observational cohort study the incidence of CDI and assess potential clinical characteristics and biomarkers to predict CDI in 1,007 patients ≥ 50 years receiving newly initiated antibiotic treatment with penicillins plus a beta-lactamase inhibitor, 3/4 generation cephalosporins, carbapenems, fluoroquinolones or clindamycin from 34 European hospitals. The estimated 90-day cumulative incidences of a first CDI episode is 1.

Trends in the Staff's Perception of Patient Safety Culture in Romanian Hospitals.

Introduction: The IRIS-2 project (2019) expanded the application of the HSOPSC in Romanian hospitals, yet applied, for the first time in the country, in 2014 (IRIS-1). The aim is an update on patient safety culture for staff, by geographic region and overall, by year of survey.

Materials And Methods: A cross-sectional study was carried out in voluntary staff in four hospitals in four regions (n.

Chronic thrombotic scarring in patients with acute deep venous thrombosis of the lower limbs.

Unlabelled: Some patients with acute deep venous thrombosis of the lower limbs may present risk factors for recurrent disease.

Aims: To analyze the most important conditions related to recurrent deep venous thrombosis of the lower limbs, other than thrombophilias.

Patients And Methods: We examined 88 consecutive patients (47 males-53.