Treatment of primary vulvar paget disease with 5% imiquimod cream.

Introduction: Our objective was to evaluate the efficacy of conservative treatment with imiquimod in Paget vulvar disease.

Materials And Methods: We describe a case series that includes 10 patients with histopathologic diagnosis of extramammary Paget disease of the vulva, who were treated with 5% imiquimod cream. Of these patients, 3 were treated for recurrent disease and 7 were treated for initial primary disease.