Publications by authors named "Delattre B"

Introduction: Penectomy, whether partial (PP) or radical (RP), are mainly performed for oncological reason. It is a rare but impactful surgery, with significant bio-psycho-social consequences. As some countries moves towards centralization to improve patient outcomes, a demographic analysis of current management in France is needed.

View Article and Find Full Text PDF

: T1 relaxation time has been shown to be valuable in detecting and characterizing tumors in various organs. This study aims to determine whether native T1 relaxation time can serve as a useful tool in distinguishing sarcomas from benign tumors. : In this retrospective study, patients with histologically confirmed soft tissue sarcomas and benign tumors were included.

View Article and Find Full Text PDF

Objectives: The aim of this study was to evaluate the diagnostic performance, image quality, and inter- and intra-observer agreement of the 3D T1 multi-echo fast field echo (mFFE) sequence in cervico-thoraco-lumbar vertebral fractures compared with conventional computed tomography (CT) as the gold standard.

Methods: We conducted a prospective single-centre study including 29 patients who underwent spinal magnetic resonance imaging (MRI) at the surgeon's request, in addition to CT for vertebral fracture assessment and classification. A 3D T1 mFFE sequence was added to the standard MRI protocol.

View Article and Find Full Text PDF
Article Synopsis
  • Chemotherapy with carboplatin and etoposide (CE) is often used for metastatic prostate cancer, but the actual benefits are not well documented in recent studies.
  • A study analyzed the effects of CE on 69 patients, showing limited efficacy, especially in heavily pretreated adenocarcinoma patients, with a PSA response in only 15.8% of cases and differing survival rates based on neuroendocrine marker status.
  • The findings suggest that combining different types of metastatic prostate cancer for treatment evaluation may not be appropriate, as CE chemotherapy appears to have a poor risk-benefit balance, marked by high toxicity and low response rates in heavily treated patients.
View Article and Find Full Text PDF

Introduction: Synthetic magnetic resonance imaging (SyMRI) is a novel quantitative and qualitative technique that permits the reconstruction of multiple image contrasts and quantitative maps from a single scan, thereby providing quantitative information and reducing scan times. The purpose of this study is to characterize intracranial meningiomas using SyMRI.

Methods: The study included 35 patients with meningiomas (6 males, 29 females; mean age 61 ± 17 years; range 21-90 years).

View Article and Find Full Text PDF

Objective: To investigate if the presence of metallic markers (markers) influences the diagnostic accuracy of preoperative breast MRI for the prediction of pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in breast cancer patients.

Materials And Methods: In this single-center, retrospective, observational study approved by the IRB of our institution, we included all consecutive patients that underwent preoperative breast MRI after completion of NAC (Mean 4,4 days ± 15,9). The presence or absence of markers, the type of markers, the size and type of artefact on each MRI sequence were recorded.

View Article and Find Full Text PDF

Anatomical studies on the radial side of the scaphoid mention inter-ligamentous connections, but without detailed description of their relations to one another. The purpose of this study was to provide an anatomical and radiological description of the ligamentous structure on the radial side of the scaphoid. High-field 3-Tesla 3D MRI scans of 7 cadaveric formaldehyde-fixed wrists were performed to assess the presence and location of each ligament.

View Article and Find Full Text PDF

Background And Purpose: Controversy exists as to whether ADC histograms are capable to distinguish human papillomavirus-positive (HPV+) from human papillomavirus-negative (HPV-) oropharyngeal squamous cell carcinoma. We investigated how the choice of b-values influences the capability of ADC histograms to distinguish between the two tumor types.

Materials And Methods: Thirty-four consecutive patients with histologically proved primary oropharyngeal squamous cell carcinoma (11 HPV+ and 23 HPV-) underwent 3T MR imaging with a single-shot EPI DWI sequence with 6 b-values (0, 50, 100, 500, 750, 1000 s/mm).

View Article and Find Full Text PDF

Spinal infections are very commonly encountered by radiologists in their routine clinical practice. In case of typical MRI features, the diagnosis is relatively easy to interpret, all the more so if the clinical and laboratory findings are in agreement with the radiological findings. In many cases, the radiologist is able to make the right diagnosis, thereby avoiding a disco-vertebral biopsy, which is technically challenging and associated with a risk of negative results.

View Article and Find Full Text PDF

Background: Synthetic MRI (SyMRI) is a quantitative technique that allows measurements of T1 and T2 relaxation times (RTs). Brain RT evolution across lifespan is well described for the younger population. The aim was to study RTs of brain parenchyma in a healthy geriatric population in order to define the normal value of structures in this group population.

View Article and Find Full Text PDF

Background And Purpose: The main purpose of this retrospective study was to evaluate inter-software variability in patients affected of a high-grade glioma for the post-processing of dynamic susceptibility contrast (DSC) perfusion imaging in MRI. MATERIALS AND METHODS: The included patients were either anaplastic astrocytoma (WHO grade III) or glioblastoma (WHO grade IV) located in the cerebral parenchyma. The postprocessing of 54 MRI-DSC imaging from 46 patients using both Intellispace.

View Article and Find Full Text PDF

Objectives: Embolic ischemic strokes cause significant mortality and morbidity worldwide. It has been proposed that some of these strokes are due to unstable carotid plaques with intraplaque hemorrhage (IPH) but a low overall degree of stenosis. Our aim was to test a fat-saturated T1-weighted (T1WI) black-blood sequence on MRI for the detection of IPH in symptomatic individuals and to quantify the relation between IPH, severity of stenoses, and ischemic brain lesions.

View Article and Find Full Text PDF

Objective: To evaluate the value of synthetic magnetic resonance imaging (MRI) and T2 mapping in distinguishing between different types of fillers in soft tissues.

Materials And Methods: Ex vivo fillers of buttock soft tissues (silicone, collagen, and different types of hyaluronic acid) were scanned using a synthetic MRI sequence at 1.5 and 3 T and an optimized T2 mapping sequence to measure the T2 relaxation times of the fillers ex vivo.

View Article and Find Full Text PDF

Background: Computational fluid dynamics (CFD) has become a popular tool for studying 'patient-specific' blood flow dynamics in cerebral aneurysms; however, rarely are the inflow boundary conditions patient-specific. We aimed to test the impact of widespread reliance on generalized inflow rates.

Methods: Internal carotid artery (ICA) flow rates were measured via 2D cine phase-contrast MRI for 24 patients scheduled for endovascular therapy of an ICA aneurysm.

View Article and Find Full Text PDF

Background: Global health systems are shifting toward value-based health care to improve patient outcomes in the face of rising health care costs. The challenge is to identify standardized outcome measurements that allow optimal quality-of-care monitoring and comparison to optimize medical practices and patient pathways. A common outcomes definition is required, including medical results (Clinical Reported Outcomes Measurements [CROMs]) and quality-of-life components that matter most to patients (Patient-Reported Outcomes Measurements [PROMs]), which are particularly important for severe pathologies with short life expectancy such as pancreatic cancer.

View Article and Find Full Text PDF

Background And Purpose: Flow diverter-induced hemodynamic change plays an important role in the mechanism of intracranial aneurysm occlusion. Our aim was to explore the relationship between aneurysm features and flow-diverter treatment of unruptured sidewall intracranial aneurysms.

Materials And Methods: MR imaging, 4D phase-contrast, was prospectively performed before flow diverter implantation in each patient with unruptured intracranial aneurysm.

View Article and Find Full Text PDF

Purpose: The goal of our study was to describe general practitioner's (GP) practice regarding prostate cancer screening, the prescribing of prostate MRI and to investigate the factors associated with the prescribing of prostate MRI (pMRI).

Methods: A survey was addressed to 1127 GP of the "Bourgogne-Franche Comté" region before the new CCAFU's guidelines publication.

Results: 93 practitioners responded, giving a response rate of 8.

View Article and Find Full Text PDF

Background And Purpose: Flow-diverter stents are widely used for the treatment of wide-neck intracranial aneurysms. Various parameters may influence intracranial aneurysm thrombosis, including the flow reduction induced by flow-diverter stent implantation, which is assumed to play a leading role. However, its actual impact remains unclear due to the lack of detailed intra-aneurysmal flow measurements.

View Article and Find Full Text PDF

Objectives: The aim was to evaluate the image quality and sensitivity to artifacts of compressed sensing (CS) acceleration technique, applied to 3D or breath-hold sequences in different clinical applications from brain to knee.

Methods: CS with an acceleration from 30 to 60% and conventional MRI sequences were performed in 10 different applications in 107 patients, leading to 120 comparisons. Readers were blinded to the technique for quantitative (contrast-to-noise ratio or functional measurements for cardiac cine) and qualitative (image quality, artifacts, diagnostic findings, and preference) image analyses.

View Article and Find Full Text PDF

Purpose: To assess knee health in retired female football players, using magnetic resonance imaging (MRI) and self-report. The focus of analysis were degenerative changes of the tibiofemoral joint, and their relationship to osteoarthritis symptoms and previous knee injury.

Methods: Forty-nine retired elite, female football players (98 knees) aged 37 years on average participated.

View Article and Find Full Text PDF

Patient-specific inflow rates are rarely available for computational fluid dynamics (CFD) studies of intracranial aneurysms. Instead, inflow rates are often estimated from parent artery diameters via power laws, i.e.

View Article and Find Full Text PDF

Background And Purpose: Synthetic MR imaging is a method that can produce multiple contrasts from a single sequence, as well as quantitative maps. Our aim was to determine the feasibility of a synthetic MR image for spine imaging.

Materials And Methods: Thirty-eight patients with clinical indications of infectious, degenerative, and neoplastic disease underwent an MR imaging of the spine (11 cervical, 8 dorsal, and 19 lumbosacral MR imaging studies).

View Article and Find Full Text PDF

Purpose: The morphological and hemodynamic evaluations of neurovascular diseases treated with stents would benefit from noninvasive imaging techniques such as 3D time-of-flight MRI (3D-TOF) and 3D phase contrast MRI (3D-PCMRI). For this purpose, a comprehensive evaluation of the stent artifacts and their impact on the flow measurement is critical.

Methods: The artifacts of a representative sample of neurovascular stents were evaluated in vitro with 3D-TOF and 3D-PCMRI sequences.

View Article and Find Full Text PDF

Unlabelled: In this article, we illustrate the main advanced magnetic resonance imaging (MRI) techniques used for imaging of the spine and spinal cord in children and adults. This work focuses on daily clinical practice and aims to address the most common questions and needs of radiologists. We will also provide tips to solve common problems with which we were confronted.

View Article and Find Full Text PDF