Publications by authors named "Delali S Degue"
Moderate corneal alkali burns such as those sustained from accidental exposure to household chemicals are treated with topical corticosteroids. Side effects include increased intraocular pressure and slowing of wound healing. Here, we compare the effects of a cannabinoid receptor 2 (CB2r) agonist, TA-A001, that is involved in wound healing with that of the corticosteroid, prednisolone.
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- Severe HSV-1 infections can lead to blindness and complications with cornea transplants, prompting research into alternative treatments.* -
- The study focused on using biosynthetic implants made from collagen and modified nanoparticles that deliver KR12, a non-toxic peptide capable of blocking HSV-1 reactivation and promoting tissue regeneration.* -
- Although the implants did not significantly reduce HSV-1 viral levels or inflammation, they successfully decreased viral spread and facilitated healing in infected rabbit corneas over a 6-month period.*